18259-05-7Relevant articles and documents
Suzuki cross-coupling of hexachlorobenzene promoted by the Buchwald ligands
Burukin, A. S.,Vasil’ev, A. A.,Zhdankina, G. M.,Zlotin, S. G.
, p. 169 - 172 (2022/02/17)
The study of cross-coupling between hexachlorobenzene and phenylboronic acid comprised five Buchwald ligands, from which 2-dicyclohexylphosphino-2′-(dimethylamino)biphenyl (DavePHOS) provided the best conversion. When excess of phenylboronic acid was used, a mixture of isomeric tri-, tetra- and pentaphenyl-substituted derivatives in the ~10:70:20 ratio was obtained, along with minor amounts of hydrodechlorination products.
Cross-coupling of polychloroarenes with phenylboronic acid and organozinc compounds catalyzed by palladium complexes
Burukin,Vasil'ev,Chizhov,Zlotin
, p. 970 - 974 (2007/10/03)
Hexachlorobenzene and 1,2,4,5-tetrachlorobenzene react with phenylboronic acid by a C-C cross-coupling mechanism with a Pd(dba)2/P(Bu t)3 system (dba is dibenzylideneacetone) or palladium-azole complexes as catalysts, or with organozinc compounds in the presence of Pd(PPh3)4 to afford substitution products of one or two chlorine atoms in moderate yields.