183133-98-4

Basic information

• Product Name: 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-11-hydroxy-6-methoxy-4a,8,13,13-tetramethyl-4,9-bis[(triethyl silyl)oxy]-, [2aR-(2aa,4b,4ab,6b,9a,11a,12a,12aa,12ba)]-
• CAS NO: 183133-98-4
• Molecular Formula: C42H66O10Si2
• Molecular Weight: 787.151
• Mol File: 183133-98-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-11-hydroxy-6-methoxy-4a,8,13,13-tetramethyl-4,9-bis[(triethyl silyl)oxy]-, [2aR-(2aa,4b,4ab,6b,9a,11a,12a,12aa,12ba)]-(CAS DataBase Reference)
• NIST Chemistry Reference: 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-11-hydroxy-6-methoxy-4a,8,13,13-tetramethyl-4,9-bis[(triethyl silyl)oxy]-, [2aR-(2aa,4b,4ab,6b,9a,11a,12a,12aa,12ba)]-(183133-98-4)
• EPA Substance Registry System: 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-11-hydroxy-6-methoxy-4a,8,13,13-tetramethyl-4,9-bis[(triethyl silyl)oxy]-, [2aR-(2aa,4b,4ab,6b,9a,11a,12a,12aa,12ba)]-(183133-98-4)

Safety Data

• Hazardous Substances Data: 183133-98-4(Hazardous Substances Data)

Upstream product

• 183133-99-5 4α-acetoxy-2α-benzoyloxy-5β,20-epoxy-1β,10β-dihydroxy-9-oxo-7β,13α-di(triethylsilyloxy)-11-taxene 
• 74-88-4 methyl iodide 
• 32981-86-5 10-deacetylbaccatin III 
• 994-30-9 triethylsilyl chloride 

Downstream Products

• 183133-94-0 4α-acetoxy-2α-benzoyloxy-5β,20-epoxy-1β,13α-dihydroxy-7β,10β-dimethoxy-9-oxo-11-taxene 
• 1433749-82-6 4α-acetoxy-2α-benzoyloxy-5β,20-epoxy-1β,7β-dihydroxy-9-oxo-10β-methoxy-13α-triethylsilyloxy-11-taxene 
• 1396601-24-3 4α-acetoxy-2α-benzoyloxy-5β,20-epoxy-1β-hydroxy-7β,10β-dimethoxy-9-oxo-13-(triethylsilyloxy)-11-taxene 
• 183133-96-2 carbazitaxel 
• 1402820-62-5 (αR, βS)-α-hydroxy-β-[[(1,1-dimethylethoxy)carbonyl]amino]benzene-propanoic acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,1112,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester isopropanol solvate 
• 183133-97-3 4α-acetoxy-2α-benzoyloxy-5β,20-epoxy-10β-methoxy-9-oxo-1β,13α,7β-trihydroxy-11-taxene 

Relevant articles and documents

PROCESS FOR THE PREPARATION CABAZITAXEL

The present invention discloses a process for the preparation of 4-acetoxy-2α-benzoyloxy-5β,20-epoxy-1-hydroxy-7β,10β-dimethoxy-9-oxotax-11-en-13α-yl(2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionate Cabazitaxel (I).