18343-02-7

Basic information

• Product Name: ethyl 3-(2-ethoxy-2-oxoethoxy)isonicotinate
• Synonyms: ethyl 3-(2-ethoxy-2-oxoethoxy)isonicotinate;Ethyl 3-(2-ethoxy-2-oxo-ethoxy)pyridine-4-carboxylate
• CAS NO: 18343-02-7
• Molecular Formula: C12H15NO5
• Molecular Weight: 253.2512
• Mol File: 18343-02-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 359.6±27.0 °C(Predicted)
• Appearance: /
• Density: 1.183±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 2.53±0.10(Predicted)
• CAS DataBase Reference: ethyl 3-(2-ethoxy-2-oxoethoxy)isonicotinate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-(2-ethoxy-2-oxoethoxy)isonicotinate(18343-02-7)
• EPA Substance Registry System: ethyl 3-(2-ethoxy-2-oxoethoxy)isonicotinate(18343-02-7)

Safety Data

• Hazardous Substances Data: 18343-02-7(Hazardous Substances Data)

Usage

General Description

Ethyl 3-(2-ethoxy-2-oxoethoxy)isonicotinate is a chemical compound with the molecular formula C14H19NO6. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. ethyl 3-(2-ethoxy-2-oxoethoxy)isonicotinate belongs to the class of organic compounds known as pyridinecarboxylic acids, and is widely utilized in the pharmaceutical industry due to its potential therapeutic effects. It is also known for its ability to inhibit the growth of certain harmful microorganisms. Additionally, it is used as a building block in the production of various drugs and is considered an important chemical in the field of medicinal chemistry.

Upstream product

• 18342-97-7 ethyl 3-hydroxyisonicotinate 
• 141-78-6 ethyl acetate 
• 10128-71-9 3-hydroxyisonicotinic acid 
• 623-50-7 ethyl 2-hydroxyacetate 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 1453175-37-5 furo[2,3-c]pyridine-2-carboxylic acid 4-(1-isobutylpiperidine-4-sulfinyl)benzylamide 
• 1453173-84-6 N-[(4-tetrahydropyran-4-ylsulfonylphenyl)methyl]furo[2,3-c]pyridine-2-carboxamide 
• 927804-63-5 ethyl 3-(((trifluoromethyl) sulfonyl)oxy)furo[2,3-c]pyridine-2-carboxylate 
• 138173-83-8 Ethyl furo<2,3-c>pyridine-2-carboxylate 
• 112372-15-3 furo<2,3-c>pyridine-2-carboxylic acid 
• 1453174-07-6 N-[[4-[(1-tetrahydropyran-4-yl-4-piperidyl)sulfonyl]phenyl]methyl]furo[2,3-c]pyridine-2-carboxamide 
• 465531-08-2 furo[2,3-c]pyridine-2-carbonyl chloride 
• 1453176-78-7 furo[2,3-c]pyridine-2-carboxylic acid benzylamide 
• 1453176-79-8 4-{[(furo[2,3-c]pyridine-2-carbonyl)-amino]-methyl}-benzenesulfonyl chloride 
• 1453175-46-6 C₂₄H₂₉N₃O₃S 
• 1453175-45-5 C₂₄H₂₉N₃O₃S 
• 1448536-37-5 N-{[4-(piperidine-1-sulfonyl)phenyl]methyl}furo[2,3-c]pyridine-2-carboxamide 
• 1454284-75-3 N-(4-(6-methylpyridin-3-ylsulfonyl)benzyl)furo[2.3-c]pyridine-2-carboxamide 
• 1454284-57-1 furo[2,3-c]pyridine-2-carboxylic acid 4-(tetrahydropyran-4-ylsulfamoyl)benzylamide 

Relevant articles and documents

AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES

The present invention relates to certain amido-benzyl sulfoxide and sulfone compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.

AMIDO-BENZYL SULFONE AND SULFONAMIDE DERIVATIVES

Disclosed are certain amido-benzyl sulfone and sulfonamide compounds, pharmaceutical compositions comprising such compounds, land methods of treatment using such compounds.

The discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors

Virtual and high-throughput screening identified imidazo[1,2-a]pyrazines as inhibitors of B-Raf. We describe the rationale, SAR, and evolution of the initial hits to a series of furo[2,3-c]pyridine indanone oximes as highly potent and selective inhibitors