1835759-73-3

Basic information

• Product Name: 1,1,1-Trifluoroethyl-PEG3-Propargyl
• Synonyms: 1,1,1-Trifluoroethyl-PEG3-Propargyl
• CAS NO: 1835759-73-3
• Molecular Formula: C9H13F3O3
• Molecular Weight: 226.1929296
• Mol File: 1835759-73-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,1,1-Trifluoroethyl-PEG3-Propargyl(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1-Trifluoroethyl-PEG3-Propargyl(1835759-73-3)
• EPA Substance Registry System: 1,1,1-Trifluoroethyl-PEG3-Propargyl(1835759-73-3)

Safety Data

• Hazardous Substances Data: 1835759-73-3(Hazardous Substances Data)

Usage

Description

1,1,1-Trifluoroethyl-PEG3-Propargyl is a heterobifunctional reagent that features an alkyne group and a trifluoroethyl group. The alkyne group is capable of reacting with azide compounds or biomolecules through copper-catalyzed Click Chemistry, resulting in the formation of a stable triazole linkage. Meanwhile, the trifluoroethyl group can react with lysine and other primary amine groups present in proteins, antibodies, and various molecules and surfaces.

Uses

Used in Bioconjugation:
1,1,1-Trifluoroethyl-PEG3-Propargyl serves as a bioconjugation agent for the attachment of proteins, antibodies, and other molecules to surfaces or other biomolecules. The trifluoroethyl group enables selective modification of primary amine groups, while the alkyne group allows for copper-catalyzed Click Chemistry with azide-containing species.
Used in Drug Delivery Systems:
In the pharmaceutical industry, 1,1,1-Trifluoroethyl-PEG3-Propargyl is used as a component in drug delivery systems to improve the targeting and efficacy of therapeutic agents. The reagent can be employed to attach drugs to nanoparticles or other carriers, facilitating their delivery to specific cells or tissues.
Used in Surface Modification:
1,1,1-Trifluoroethyl-PEG3-Propargyl is utilized in the modification of surfaces, such as in the development of biosensors or lab-on-a-chip devices. The trifluoroethyl group can be used to immobilize proteins or other biomolecules onto surfaces, while the alkyne group can be employed for further functionalization through Click Chemistry.
Used in Polymer Science:
In polymer science, 1,1,1-Trifluoroethyl-PEG3-Propargyl is used as a building block for the synthesis of functional polymers. The reagent can be incorporated into polymer structures to provide specific properties, such as enhanced solubility, stability, or biocompatibility.
Used in Chemical Biology:
1,1,1-Trifluoroethyl-PEG3-Propargyl is employed in chemical biology for the study of protein-protein interactions, enzyme activity, and other biological processes. The reagent can be used to label proteins or other biomolecules with tags that enable their detection, visualization, or manipulation.