183625-23-2

Basic information

• Product Name: 2-Hexenoic acid, 5-hydroxy-4-(phenylmethoxy)-, methyl ester, (2E,4S,5R)-
• CAS NO: 183625-23-2
• Molecular Formula: C14H18O4
• Molecular Weight: 250.295
• Mol File: 183625-23-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Hexenoic acid, 5-hydroxy-4-(phenylmethoxy)-, methyl ester, (2E,4S,5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hexenoic acid, 5-hydroxy-4-(phenylmethoxy)-, methyl ester, (2E,4S,5R)-(183625-23-2)
• EPA Substance Registry System: 2-Hexenoic acid, 5-hydroxy-4-(phenylmethoxy)-, methyl ester, (2E,4S,5R)-(183625-23-2)

Safety Data

• Hazardous Substances Data: 183625-23-2(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 51830-12-7 Epoxy-4,5 hexene-2 (E) oate de methyle 
• 79-22-1 methyl chloroformate 

Downstream Products

• 931426-03-8 (+)-(4S,5R)-4-benzyloxy-5-hydroxy-(2E)-hexenoic acid 
• 183479-31-4 (E)-(4S,5R)-4-Hydroxy-5-(toluene-4-sulfonyloxy)-hex-2-enoic acid methyl ester 
• 294198-62-2 (E)-(4S,5R)-4-Benzyloxy-5-[(R)-3-(tert-butyl-dimethyl-silanyloxy)-butyryloxy]-hex-2-enoic acid (E)-(1R,2S)-2-benzyloxy-1-methyl-4-(2,2,2-trichloro-ethoxycarbonyl)-but-3-enyl ester 
• 294198-63-3 (E)-(4S,5R)-4-Benzyloxy-5-((R)-3-hydroxy-butyryloxy)-hex-2-enoic acid (E)-(1R,2S)-2-benzyloxy-1-methyl-4-(2,2,2-trichloro-ethoxycarbonyl)-but-3-enyl ester 
• 294198-60-0 (E)-(4S,5R)-4-Benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-hex-2-enoic acid (E)-(1R,2S)-2-benzyloxy-1-methyl-4-(2,2,2-trichloro-ethoxycarbonyl)-but-3-enyl ester 
• 294198-61-1 (E)-(4S,5R)-4-Benzyloxy-5-hydroxy-hex-2-enoic acid (E)-(1R,2S)-2-benzyloxy-1-methyl-4-(2,2,2-trichloro-ethoxycarbonyl)-but-3-enyl ester 
• 294198-64-4 (+)-dibenzyl macrosphelide A 
• 294198-58-6 (4S,5R)-4-benzyloxy-5-tert-butyldimethylsilyloxy-2(E)-hexenoic acid 
• 294198-59-7 2,2,2-trichloroethyl (4S,5R)-4-benzyloxy-5-hydroxy-2(E)-hexenoate 
• 931426-04-9 (4S,5R)-4-benzyloxy-2-hexen-5-olide 
• 183479-32-5 (E)-(4S,5S)-4-Benzyloxy-5-chloro-hex-2-enoic acid methyl ester 
• 183479-30-3 (E)-(4S,5R)-4-Benzyloxy-5-(toluene-4-sulfonyloxy)-hex-2-enoic acid methyl ester 

Relevant articles and documents

δ-Lactone formation from δ-hydroxy-trans-α,β-unsaturated carboxylic acids accompanied by trans-cis isomerization: synthesis of (-)-tetra-O-acetylosmundalin

(±)-(4,5-anti)-4-Benzyloxy-5-hydroxy-(2E)-hexenoic acid 6 was subjected to δ-lactonization in the presence of 2,4,6-trichlorobenzoyl chloride and pyridine to give the α,β-unsaturated-δ-lactone congener (±)-7 (87% yield) accompanied by trans-cis isomerizat