184041-14-3

Basic information

• Product Name: N-{5-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonyl}pyrrole
• Synonyms: N-{5-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonyl}pyrrole
• CAS NO: 184041-14-3
• Molecular Weight: 357.377
• Mol File: 184041-14-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-{5-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonyl}pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: N-{5-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonyl}pyrrole(184041-14-3)
• EPA Substance Registry System: N-{5-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonyl}pyrrole(184041-14-3)

Safety Data

• Hazardous Substances Data: 184041-14-3(Hazardous Substances Data)

Upstream product

• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 166964-01-8 N-(5-Bromothiophene-2-sulfonyl)-pyrrole 

Downstream Products

• 184041-16-5 2-chlorosulfonyl-5-[4-(trifluoromethyl)phenyl]thiophene 

Relevant articles and documents

N-aryl thienyl-, furyl-, and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin

Thienyl-, furyl- and pyrrolyl-sulfonamides and methods for modulating or altering the activity of the endothelin family of peptides are provided. In particular, N-(isoxazolyl)thienylsulfonamides, N-(isoxazolyl)furylsulfonamides and N-(isoxazolyl)pyrrolylsulfonamides and methods using these sulfonamides for inhibiting the binding of an endothelin peptide to an endothelin receptor by contacting the receptor with the sulfonamide are provided. Methods for treating endothelin-mediated disorders by administering effective amounts of one or more of these sulfonamides or prodrugs thereof that inhibit or increase the activity of endothelin are also provided.