1845-11-0Relevant articles and documents
Copper-catalyzed carboarylation of alkynes via vinyl cations
Walkinshaw, Andrew J.,Xu, Wenshu,Suero, Marcos G.,Gaunt, Matthew J.
supporting information, p. 12532 - 12535 (2013/09/23)
Copper-catalyzed arylation of electron rich alkynes reveals stabilized trisubstituted vinyl cation equivalents that react with pendant arene nucleophiles to form all carbon tetrasubstituted alkenes. The new process streamlines the synthesis of important medicinally relevant molecules.
Process for the preparation of alfa-substituted ketones and their application in synthesis of pharmaceutically active compounds
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Page/Page column 14, (2012/12/13)
The present invention relates to a novel one step preparation of 6-methoxy-2-phenyl-tetralone starting from 6-methoxy-tetralone and its use as an intermediate in the synthesis of pharmaceutically active compounds.
A PROCESS FOR THE PREPARATION OF LASOFOXIFENE TARTRATE
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Page/Page column 20; 21, (2010/11/17)
The present invention relates to solid state chemistry of 1-(2-[4-(6-methoxy-3,4-dihydronaphthalene-1-yl) phenoxy]ethyl)pyrrolidine, a process for its preparation and its use as an intermediate in the synthesis of lasofoxifene.