1848337-06-3 Usage
Description
2-[((4-[([(hexyloxy)carbonyl]amino)methanimidoyl]phenyl)amino)methyl]-1-methyl-1H-benzimidazole-5-carboxylic acid is a complex organic compound with a unique chemical structure. It is a degradation product of Dabigatran (D100090), a nonpeptide, direct thrombin inhibitor and an antithrombotic drug. 2-[((4-[([(hexyloxy)carbonyl]amino)methanimidoyl]phenyl)amino)methyl]-1-methyl-1H-benzimidazole-5-carboxylic acid is characterized by its benzimidazole core, with various functional groups attached, including a hexyloxycarbonyl group and an aminomethanimidoyl group. Its molecular structure endows it with specific properties that make it suitable for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
2-[((4-[([(hexyloxy)carbonyl]amino)methanimidoyl]phenyl)amino)methyl]-1-methyl-1H-benzimidazole-5-carboxylic acid is used as an intermediate compound in the synthesis of Dabigatran, a direct thrombin inhibitor and antithrombotic drug. Its role in the pharmaceutical industry is crucial for the development and production of Dabigatran, which is used to prevent blood clots and treat conditions such as atrial fibrillation, deep vein thrombosis, and pulmonary embolism.
Used in Research and Development:
In the field of research and development, 2-[((4-[([(hexyloxy)carbonyl]amino)methanimidoyl]phenyl)amino)methyl]-1-methyl-1H-benzimidazole-5-carboxylic acid serves as a valuable compound for studying the structure-activity relationships of thrombin inhibitors. Its unique chemical structure allows researchers to explore new avenues in drug design and develop novel therapeutic agents with improved efficacy and safety profiles.
Used in Quality Control and Analytical Chemistry:
2-[((4-[([(hexyloxy)carbonyl]amino)methanimidoyl]phenyl)amino)methyl]-1-methyl-1H-benzimidazole-5-carboxylic acid can be employed as a reference compound in quality control and analytical chemistry. Its distinct chemical properties make it suitable for use as a standard or control sample in various analytical techniques, such as high-performance liquid chromatography (HPLC), mass spectrometry, and nuclear magnetic resonance (NMR) spectroscopy. This helps ensure the accuracy and reliability of these methods in the analysis of related compounds and pharmaceutical products.
Check Digit Verification of cas no
The CAS Registry Mumber 1848337-06-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,4,8,3,3 and 7 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1848337-06:
(9*1)+(8*8)+(7*4)+(6*8)+(5*3)+(4*3)+(3*7)+(2*0)+(1*6)=203
203 % 10 = 3
So 1848337-06-3 is a valid CAS Registry Number.
1848337-06-3Relevant articles and documents
Dabigatran etexilate intermediate synthesis method
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, (2016/12/22)
The invention discloses dabigatran etexilate, an intermediate thereof with a formula (5), and a synthesis method of a derivative thereof. According to the synthesis method, a compound represented by a formula (2) is subjected to a compound represented by a formula (4), such that a compound represented by the formula (5) is obtained; the compound represented by the formula (5) is hydrolyzed, and is subjected to a reaction with 3-(pyridin-2-ylamino)ethyl propionate, such that dabigatran etexilate is prepared.
