184838-77-5Relevant articles and documents
Synthesis of enantiopure pseudo-L-vinylcyclopropyl nucleosides bearing quaternary carbon as potential anti-herpesvirus agent
Moon, Hyung Ryong,Park, Ah-Young,Kim, Kyung Ran,Chun, Moon Woo,Jeong, Lak Shin
, p. 975 - 978 (2007)
Pseudo-l-vinylcyclopropyl adenine and guanine nucleosides 11 and 12 were designed and enantiopurely synthesized starting from (S)-epichlorohydrin using tandem alkylation, regioselective oxirane-ring opening, and chemoselective reduction as key steps. Copy
PRORENIN RECEPTOR LIGAND AND ANTAGONIST
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Paragraph 0050-0051, (2017/10/26)
PROBLEM TO BE SOLVED: To design and synthesize β strand mimetics using structural characteristics of cyclopropane and provide a new (pro)renin receptor ligand, and also provide a new (pro)renin receptor inhibitor that is excellent in solubility, stability
Three-dimensional structural diversity-oriented peptidomimetics based on the cyclopropylic strain
Mizuno, Akira,Miura, Shiho,Watanabe, Mizuki,Ito, Yoshihiko,Yamada, Shizuo,Odagami, Takenao,Kogami, Yuji,Arisawa, Mitsuhiro,Shuto, Satoshi
supporting information, p. 1686 - 1689 (2013/07/05)
Conformationally restricted peptidomimetics comprising eight stereoisomeric scaffolds with three-dimensional structural diversity were designed based on the structural features of cyclopropane, that is, cyclopropylic strain, which mimic wide-ranging tetra
PHTALAZINONE DERIVATIVES AS MPEGS -1 INHIBITORS
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Page/Page column 59; 60, (2013/06/05)
The present patent application is directed to bicyclic compounds of formula (I) or pharmaceutically acceptable salt thereof as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (m PGES-1) enzyme and are theref