185057-00-5Relevant articles and documents
Quinoline and Isoquinoline Based HDAC Inhibitors and Methods of Use Thereof
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Paragraph 0173; 0178, (2019/09/16)
The present invention relates to methods of modulating activity of histone deacetylases (HDACs). The present invention also relates to methods of treating HDAC-associated diseases including, but not limited to, cancers, inflammatory disorders, and neurode
Azacyclic derivative as well as preparation method and medical use thereof
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Paragraph 0376; 0377; 0378; 0388; 0389, (2019/02/04)
The invention relates to an azacyclic derivative as well as a preparation method and medical use thereof and particularly relates to an azacyclic derivative represented by a general formula (I) (shownin the description), a preparation method thereof, a pharmaceutical composition containing the derivative and use of the derivative as an SMO antagonist, particularly in the treatment of diseases such as cancer related to Hedgehog signal channels. The definitions of groups in the general formula (I) are same as the definitions in the description.
Pyrrolo pyrimidine ring compound, its use and pharmaceutical composition (by machine translation)
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Page/Page column 61; 62, (2017/07/31)
The invention relates to an as TLR7 agonist of the pyrrolo pyrimidine compounds, specifically on a compound of formula (I) compound or its pharmaceutically acceptable salt, preparation method thereof, containing the compounds of the pharmaceutical composition, and its use for the preparation of antiviral drug use. Formula (I) (by machine translation)