185250-14-0

Basic information

• Product Name: N,N'-Bis-(3-{[phenyl-(4,4,5,5-tetramethyl-2-oxo-2λ⁵-[1,3,2]dioxaphospholan-2-yl)-methyl]-amino}-propyl)-butane-1,4-diamine
• CAS NO: 185250-14-0
• Molecular Weight: 706.843
• Mol File: 185250-14-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N'-Bis-(3-{[phenyl-(4,4,5,5-tetramethyl-2-oxo-2λ⁵-[1,3,2]dioxaphospholan-2-yl)-methyl]-amino}-propyl)-butane-1,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-Bis-(3-{[phenyl-(4,4,5,5-tetramethyl-2-oxo-2λ⁵-[1,3,2]dioxaphospholan-2-yl)-methyl]-amino}-propyl)-butane-1,4-diamine(185250-14-0)
• EPA Substance Registry System: N,N'-Bis-(3-{[phenyl-(4,4,5,5-tetramethyl-2-oxo-2λ⁵-[1,3,2]dioxaphospholan-2-yl)-methyl]-amino}-propyl)-butane-1,4-diamine(185250-14-0)

Safety Data

• Hazardous Substances Data: 185250-14-0(Hazardous Substances Data)

Upstream product

• 16352-18-4 4,4,5,5-tetramethyl<1,3,2>dioxaphospholane-2-oxide 
• 185250-13-9 1,1'-(butane-1,4-diyl)-2,2'-diphenylbis(hexahydropyrimidine) 
• 100-52-7 benzaldehyde 
• 71-44-3 Spermine 

Relevant articles and documents

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The reaction of spermine with aromatic aldehyde leads to an equilibrated system between the bis imine form 1′ and the hexahydropyrimidine form 1. In contrary the formaldehyde adduct of spermine exist only on the hexahydropyrimidine form 9. 1-1′ is readily hydrolyzed by HCl with regeneration of the aldehyde and spermine. The NaBH4 reduction of 1-1′ leads to the dibenzyl spermine 8 and the phosphonate adducts 2 or 6 are obtained from 1-1′ and a hydrogen phosphonate. These last two reactions failed with 9. Inversely 9 and 1-1′ reacts equably well with tetramethyl chloro dioxaphospholane with formation of cyclic phosphinamidates 10 and 5. In the second case a kinetic intermediate 3 can be observed by 31P NMR.