185685-53-4

Basic information

• Product Name: Methanone, (4-iodophenyl)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-
• CAS NO: 185685-53-4
• Molecular Formula: C21H23IO
• Molecular Weight: 418.318
• Mol File: 185685-53-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Methanone, (4-iodophenyl)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (4-iodophenyl)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-(185685-53-4)
• EPA Substance Registry System: Methanone, (4-iodophenyl)(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-(185685-53-4)

Safety Data

• Hazardous Substances Data: 185685-53-4(Hazardous Substances Data)

Upstream product

• 6683-46-1 1,1,4,4-Tetramethyl-1,2,3,4-tetrahydro-naphthalene 
• 1711-02-0 4-iodobenzoic acid chloride 

Downstream Products

• 185685-73-8 [4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalene-2-carbonyl)-phenyl]-propynoic acid methyl ester 
• 117168-45-3 (2E)-3-{4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]phenyl}prop-2-enoic acid 
• 185685-67-0 (E)-2-Methyl-3-[4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalene-2-carbonyl)-phenyl]-acrylic acid methyl ester 

Relevant articles and documents

Development and Characterization of Novel and Selective Inhibitors of Cytochrome P450 CYP26A1, the Human Liver Retinoic Acid Hydroxylase

Cytochrome P450 CYP26 enzymes are responsible for all-trans-retinoic acid (atRA) clearance. Inhibition of CYP26 enzymes will increase endogenous atRA concentrations and is an attractive therapeutic target. However, the selectivity and potency of the exist