186371-33-5

Basic information

• Product Name: 2-((S)-tert-Butoxycarbonylamino-phenyl-methyl)-acrylic acid (1R,2S)-2-phenyl-cyclohexyl ester
• Synonyms: 2-((S)-tert-Butoxycarbonylamino-phenyl-methyl)-acrylic acid (1R,2S)-2-phenyl-cyclohexyl ester
• CAS NO: 186371-33-5
• Molecular Weight: 435.563
• Mol File: 186371-33-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-((S)-tert-Butoxycarbonylamino-phenyl-methyl)-acrylic acid (1R,2S)-2-phenyl-cyclohexyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((S)-tert-Butoxycarbonylamino-phenyl-methyl)-acrylic acid (1R,2S)-2-phenyl-cyclohexyl ester(186371-33-5)
• EPA Substance Registry System: 2-((S)-tert-Butoxycarbonylamino-phenyl-methyl)-acrylic acid (1R,2S)-2-phenyl-cyclohexyl ester(186371-33-5)

Safety Data

• Hazardous Substances Data: 186371-33-5(Hazardous Substances Data)

Upstream product

• 98919-68-7 (1R,2S)-trans-2-phenylcyclohexanol 
• 150884-50-7 benzaldehyde N-boc imine 
• 186371-31-3 Propynoic acid (1R,2S)-2-phenyl-cyclohexyl ester 

Downstream Products

• 186371-28-8 C₅₀H₅₇Cl₆NO₁₉ 
• 186371-29-9 C₅₀H₅₇Cl₆NO₁₉ 
• 186371-27-7 C₅₀H₅₅Cl₆NO₁₇ 
• 186371-25-5 (S)-2-(((tert-butoxycarbonyl)amino)(phenyl)methyl)acrylic acid 

Relevant articles and documents

Effective enantioselective approach to α-aminoalkylacrylic acid derivatives via a synthetic equivalent of an asymmetric Baylis-Hillman reaction: Application to the synthesis of two C-2′ hydroxymethyl analogues of docetaxel

Two C-2′ hydroxymethyl analogues of docetaxel have been synthesized from 10-desacetyl baccatin III and enantiopure (3S)-3-(N-tert-butoxycarbonylamino)-2-methylene-3-phenylpropanoic acid; the latter was prepared via the use of a new method, which is discus