186447-05-2

Basic information

• Product Name: 2-[3-(3,4-dichlorophenyl)-5-(4-hydroxy-4-phenyl-1-piperidinyl)-1-oxopentyl]-1,2,3,4-tetrahydroisoquinoline
• Synonyms: 2-[3-(3,4-dichlorophenyl)-5-(4-hydroxy-4-phenyl-1-piperidinyl)-1-oxopentyl]-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 186447-05-2
• Molecular Weight: 537.529
• Mol File: 186447-05-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[3-(3,4-dichlorophenyl)-5-(4-hydroxy-4-phenyl-1-piperidinyl)-1-oxopentyl]-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[3-(3,4-dichlorophenyl)-5-(4-hydroxy-4-phenyl-1-piperidinyl)-1-oxopentyl]-1,2,3,4-tetrahydroisoquinoline(186447-05-2)
• EPA Substance Registry System: 2-[3-(3,4-dichlorophenyl)-5-(4-hydroxy-4-phenyl-1-piperidinyl)-1-oxopentyl]-1,2,3,4-tetrahydroisoquinoline(186447-05-2)

Safety Data

• Hazardous Substances Data: 186447-05-2(Hazardous Substances Data)

Upstream product

• 186447-56-3 2-[3-(3,4-dichlorophenyl)-1,5-dioxopentyl]-1,2,3,4-tetrahydroisoquinoline 
• 5004-94-4 4-hydroxy-4-phenylpiperidine hydrochloride 

Relevant articles and documents

Piperidine derivatives as neurokinin antagonists

The invention relates to compounds of the formula STR1 wherein X, i, j, n, n', A, A', R2, R3, and U are as described herein. The compounds of the invention are NK1 or NK2 or NK3 receptor antagonists and as such are useful in the treatment of diseases such as asthma.