18649-93-9

Basic information

• Product Name: Alisol B
• Synonyms: ALISOL B;(23S,24R)-24,25-Epoxy-11b,23-dihydroxy-8a,9b,14b-dammar-13(17)-en-3-one;(8α,9β,14β,23S,24R)-11β,23-Dihydroxy-24,25-epoxy-5α-dammar-13(17)-en-3-one
• CAS NO: 18649-93-9
• Molecular Formula: C₃₀H₄₈O₄
• Molecular Weight: 444.65
• Product Categories: Triterpenoids;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 18649-93-9.mol
• Article Data: 0

Chemical Properties

• Melting Point: 166-168 °C
• Boiling Point: 575.1°Cat760mmHg
• Flash Point: 179.1°C
• Appearance: /
• Density: 1.12g/cm³
• Vapor Pressure: 1.27E-15mmHg at 25°C
• Refractive Index: 1.553
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 14.35±0.20(Predicted)
• CAS DataBase Reference: Alisol B(CAS DataBase Reference)
• NIST Chemistry Reference: Alisol B(18649-93-9)
• EPA Substance Registry System: Alisol B(18649-93-9)

Safety Data

• Hazardous Substances Data: 18649-93-9(Hazardous Substances Data)

Usage

General Description

Alisol B is a triterpenoid compound isolated from the roots of the Alisma orientale plant. It has been found to possess various pharmacological properties, including anti-inflammatory, anti-cancer, anti-diabetic, and hepatoprotective effects. Studies have shown that Alisol B can inhibit the growth of cancer cells, reduce inflammation, and improve insulin sensitivity in diabetic individuals. Additionally, it has been found to protect the liver from damage caused by toxins and has potential in the treatment of liver diseases. Overall, Alisol B is a promising natural compound with potential therapeutic applications in various medical conditions.

InChI:InChI=1/C30H48O4/c1-17(15-21(32)25-27(4,5)34-25)18-9-13-29(7)19(18)16-20(31)24-28(6)12-11-23(33)26(2,3)22(28)10-14-30(24,29)8/h17,20-22,24-25,31-32H,9-16H2,1-8H3/t17-,20+,21?,22?,24+,25?,28+,29+,30+/m1/s1

Downstream Products

• 155521-46-3 alisol G 
• 18674-16-3 alisol A 24-acetate 

Related news

A UFLC/MS/MS method for simultaneous quantitation of alisol A and Alisol B (cas 18649-93-9) 23-acetate from Alisma orientale (Sam.) Juz. in rat plasma07/14/2019

A sensitive and reliable ultra fast liquid chromatography tandem mass spectrometry (UFLC-MS/MS) method has been developed and validated for simultaneous quantitation of alisol A and alisol B 23-acetate from Alisma orientale (Sam.) Juz. in rat plasma using diazepam as an internal standard (IS). T...detailed

Antiproliferative activity of Alisol B (cas 18649-93-9) in MDA-MB-231 cells is mediated by apoptosis, dysregulation of mitochondrial functions, cell cycle arrest and generation of reactive oxygen species07/13/2019

Previous studies have demonstrated that Alisol B has inhibitory activity in cancer cells. However, the exact mechanism through which inhibition is achieved is still poorly understood. In the present study, the authors examined the effects of Alisol B in human breast cancer cells. Alisol B showed...detailed