18671-94-8

Basic information

• Product Name: 3,7-dichloro-1,2,4-benzotriazine 1-oxide
• Synonyms: 1,2,4-benzotriazine, 3,7-dichloro-, 1-oxide; 3,7-Dichloro-1,2,4-benzotriazine 1-oxide
• CAS NO: 18671-94-8
• Molecular Formula: C₇H₃Cl₂N₃O
• Molecular Weight: 216.0242
• Mol File: 18671-94-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 423.8°C at 760 mmHg
• Flash Point: 210.1°C
• Density: 1.73g/cm³
• Vapor Pressure: 5.36E-07mmHg at 25°C
• Refractive Index: 1.733
• CAS DataBase Reference: 3,7-dichloro-1,2,4-benzotriazine 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,7-dichloro-1,2,4-benzotriazine 1-oxide(18671-94-8)
• EPA Substance Registry System: 3,7-dichloro-1,2,4-benzotriazine 1-oxide(18671-94-8)

Safety Data

• Hazardous Substances Data: 18671-94-8(Hazardous Substances Data)

Upstream product

• 20028-78-8 7-chloro-1-oxy-4H-benzo[e][1,2,4]triazin-3-one 
• 7153-86-8 (4-chloro-2-nitro-phenyl)-urea 
• 18671-92-6 7-chloro-1-oxido-1,2,4-benzotriazin-1-ium-3-amine 
• 881-51-6 N-(4-chloro-2-nitrophenyl)-acetamide 
• 106-47-8 4-chloro-aniline 
• 539-03-7 N-(4-chlorophenyl)acetamide 
• 89-63-4 4-Chloro-2-nitroaniline 
• 20028-78-8 7-chloro-1-oxido-1,2,4-benzotriazin-1-ium-3-ol 

Downstream Products

• 921933-37-1 C₁₃H₉ClN₄O 
• 921933-36-0 C₁₃H₁₅ClN₄O 
• 875850-75-2 benzyl-(7-chloro-1-oxy-benzo[e][1,2,4]triazin-3-yl)-amine 

Relevant articles and documents

MODULATORS OF THE P70S6 KINASE FOR USE IN THE TREATMENT OF BRAIN DISORDERS AND TRIPLE-NEGATIVE BREAST CANCER

The invention provides compounds for use in the treatment of a disease or condition selected from brain disorders and triple-negative breast cancer, the compounds being of the formula (1) or a salt or tautomer thereof; wherein: X1 is N or N+(O'

SUBSTITUTED BENZOTRIAZINES AND QUINOXALINES AS INHIBITORS OF P7OS6 KINASE

The invention provides compounds of the formula (1): or salts or tautomers thereof; wherein X1 is N or N+(O ); X2 is N or CH; Q is a C1-3 alkylene group; R1 is selected from hydrogen, C1-4 hydrocarbyl and hydroxy-C2-4 hydrocarbyl; R2, R3 and R4 are the same or different and each is selected from hydrogen, fluorine, chlorine and methyl; Ar1 is an optionally substituted monocyclic 5 or 6-membered aryl or heteroaryl ring containing 0, 1 or 2 heteroatom ring members selected from O, N and S, or a naphthyl ring and Ar2 is an optionally substituted monocyclic 5 or 6-membered heteroaryl ring containing 1, 2 or 3 heteroatom ring members selected from O, N and S. The compounds of formula (1) are inhibitors of p70S6 kinase and are useful in the treatment of proliferative diseases.