187084-14-6

Basic information

• Product Name: (S)-1-(3,5-Dimethoxy-phenyl)-3-methyl-pentan-1-ol
• Synonyms: (S)-1-(3,5-Dimethoxy-phenyl)-3-methyl-pentan-1-ol
• CAS NO: 187084-14-6
• Molecular Weight: 238.327
• Mol File: 187084-14-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-1-(3,5-Dimethoxy-phenyl)-3-methyl-pentan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(3,5-Dimethoxy-phenyl)-3-methyl-pentan-1-ol(187084-14-6)
• EPA Substance Registry System: (S)-1-(3,5-Dimethoxy-phenyl)-3-methyl-pentan-1-ol(187084-14-6)

Safety Data

• Hazardous Substances Data: 187084-14-6(Hazardous Substances Data)

Upstream product

• 534-00-9 (S)-2-methylbutyl bromide 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 35026-81-4 (2S)-methylbuthyl-1-magnesium bromide 

Downstream Products

• 187084-16-8 5-((S)-3-Methyl-pentyl)-benzene-1,3-diol 
• 187084-15-7 1-(3,5-dimethoxy)-3'(S)-methylpentane 

Relevant articles and documents

Side chain methyl analogues of Δ8-THC

The synthesis of both side chain epimers of 1'- (4), 2'- (5), 3'-methyl- (6) and 4'-methyl-Δ8-tetrahydrocannobinol (7) has been carried out. The synthetic approach entailed the acid catalyzed condensation of the appropriate substituted resorcinol with menthadienol to provide the Δ8-THC analogue. Both isomers of 1'- (4) and 2'-Δ8-THC (5) were more potent than Δ8-THC, both in vitro and in vivo. The 3'-methyl isomers (6) were approximately equal in potency to Δ8-THC, and 4'-methyl-Δ8-THC was less potent. There was relatively little difference in potency between the epimers of 4, 5, and 6.