1872387-85-3 Usage
Description
1-(4-(tert-butyl)phenyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea is a chemical compound with the molecular formula C24H31BN2O3. It is a urea derivative that contains both a phenyl and a boron-containing group. 1-(4-(tert-butyl)phenyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea has potential applications in various fields including pharmaceuticals, agrochemicals, and materials science. It may serve as a building block for the synthesis of more complex molecules, or as a catalyst or reagent in organic reactions. Further research and testing may be needed to fully understand and harness the potential of this compound in different applications.
Uses
Used in Pharmaceutical Industry:
1-(4-(tert-butyl)phenyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea is used as a building block for the synthesis of complex pharmaceutical molecules due to its unique structure containing both phenyl and boron-containing groups. Its potential applications in drug development could be vast, depending on the specific properties and reactivity of the compound when further investigated.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(4-(tert-butyl)phenyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea may be utilized as a component in the development of new pesticides or other agrochemical products. Its specific role would depend on its chemical properties and how it can be integrated into existing or novel chemical frameworks.
Used in Materials Science:
1-(4-(tert-butyl)phenyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea could be used in materials science for the development of new materials with unique properties. The incorporation of this compound into polymers or other materials could potentially enhance their characteristics, such as strength, durability, or chemical resistance, depending on the compound's reactivity and compatibility with other materials.
Used as a Catalyst or Reagent in Organic Reactions:
Given its structure, 1-(4-(tert-butyl)phenyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea may also find use as a catalyst or reagent in various organic reactions. Its potential to facilitate or enhance specific chemical transformations could be valuable in the synthesis of complex organic molecules, including those with pharmaceutical, agrochemical, or materials science applications. Further research would be necessary to determine its effectiveness and optimal use in these contexts.
Check Digit Verification of cas no
The CAS Registry Mumber 1872387-85-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,7,2,3,8 and 7 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1872387-85:
(9*1)+(8*8)+(7*7)+(6*2)+(5*3)+(4*8)+(3*7)+(2*8)+(1*5)=223
223 % 10 = 3
So 1872387-85-3 is a valid CAS Registry Number.
1872387-85-3Relevant articles and documents
Discovery of novel anti-angiogenesis agents. Part 8: Diaryl thiourea bearing 1H-indazole-3-amine as multi-target RTKs inhibitors
Sun, Ying,Shan, Yuanyuan,Li, Chuansheng,Si, Ru,Pan, Xiaoyan,Wang, Binghe,Zhang, Jie
, p. 373 - 385 (2017/10/16)
VEGFR-2, TIE-2, and EphB4 are essential for both angiogenesis and tumorigenesis. Herein, we designed and prepared three classes of multi-target inhibitors based on the extensive sequence homology along the kinase domain of angiogenic RTKs. Biological evaluation indicated that these multi-target inhibitors exhibited considerable potential as novel anti-angiogeneic and anticancer agents. Among them, a diaryl thiourea bearing 1H-indazole-3-amine (16a) displayed the most potent RTK inhibition and excellent selectivity. It also showed inhibition on viability of human umbilical vein endothelial cells and anti-proliferation against a broad spectrum of cancer cells. Therefore, 1H-indazole-3-amine could serve as a promising hinge binding group for multi-target inhibitors of VEGFR-2, Tie-2, and EphB4.
Arylboronic acids as dual-action FAAH and TRPV1 ligands
Morera, Enrico,Di Marzo, Vincenzo,Monti, Ludovica,Allarà, Marco,Schiano Moriello, Aniello,Nalli, Marianna,Ortar, Giorgio,De Petrocellis, Luciano
, p. 1401 - 1405 (2016/02/19)
A series of 31 arylboronic acids designed on the basis of the pharmacophore model for a variety of TRPV1 antagonists was prepared and tested on FAAH and TRPV1 channel. Four of them, that is, compounds 3c, 4a, 5a,b acted as dual FAAH/TRPV1 blockers with IC50 values between 0.56 and 8.11 μM whereas ten others (compounds 1c,f-i, 2c-f, 4b) inhibited FAAH and activated/desensitized TRPV1.
