187264-03-5Relevant articles and documents
Design, synthesis and biological evaluation of novel indole-xanthendione hybrids as selective estrogen receptor modulators
Singla, Ramit,Gupta, Kunj Bihari,Upadhyay, Shishir,Dhiman, Monisha,Jaitak, Vikas
, p. 266 - 277 (2017/12/06)
Ground breaking clinical therapeutic advances in the treatment of breast cancer (BC) is the introduction of selective estrogen receptor modulators (SERMs). We have expeditiously designed and synthesized indole-xanthendione hybrids by coalescing the indole
Identification of novel indole based heterocycles as selective estrogen receptor modulator
Singla, Ramit,Prakash, Kunal,Bihari Gupta, Kunj,Upadhyay, Shishir,Dhiman, Monisha,Jaitak, Vikas
, p. 72 - 88 (2018/05/09)
In the present study, we have designed and synthesized indole derivatives by coalescing the indole nucleus with chromene carbonitrile and dihydropyridine nucleus. Two compounds 5c and 6d were selected from series I and II after sequential combinatorial li
Fluorination-Oxidation of 2-Hydroxymethylindole Using Selectfluor
Jiang, Xiaojian,Zhang, Feng,Yang, Junjie,Yu, Pei,Yi, Peng,Sun, Yewei,Wang, Yuqiang
supporting information, p. 853 - 858 (2017/03/11)
An unexpected fluorination-oxidation of 2-hydroxymethylindole using selectfluor under mild condi-tions without a catalyst is described. This new chemistry allows for efficient and rapid synthesis of various 3-fluoroindole-2-aldehydes and novel quaternary