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18755-52-7

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18755-52-7 Usage

General Description

(2-methyl-2-phenyl-propyl) acetate, also known as "homosalate," is an organic compound commonly used as an ingredient in sunscreen and other cosmetic products. It is an ester formed from the condensation of acetic acid and (2-methyl-2-phenyl-propyl) alcohol, and it provides UVB protection by absorbing and dissipating harmful rays from the sun. Homosalate is generally well-tolerated by most individuals and is considered safe for use in personal care products when used in concentrations of up to 15%. However, there have been some concerns raised about its potential to disrupt hormone function or cause skin irritation in sensitive individuals, so it is important to consider these factors when using products containing this chemical.

Check Digit Verification of cas no

The CAS Registry Mumber 18755-52-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,7,5 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 18755-52:
(7*1)+(6*8)+(5*7)+(4*5)+(3*5)+(2*5)+(1*2)=137
137 % 10 = 7
So 18755-52-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H16O2/c1-10(13)14-9-12(2,3)11-7-5-4-6-8-11/h4-8H,9H2,1-3H3

18755-52-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-methyl-2-phenylpropyl) acetate

1.2 Other means of identification

Product number -
Other names acetic acid-(2-methyl-2-phenyl-propyl ester)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18755-52-7 SDS

18755-52-7Relevant articles and documents

Impact of Oxidation State on Reactivity and Selectivity Differences between Nickel(III) and Nickel(IV) Alkyl Complexes

Roberts, Courtney C.,Camasso, Nicole M.,Bowes, Eric G.,Sanford, Melanie S.

, p. 9104 - 9108 (2019)

Described is a systematic comparison of factors impacting the relative rates and selectivities of C(sp3)?C and C(sp3)?O bond-forming reactions at high-valent Ni as a function of oxidation state. Two Ni complexes are compared: a catio

The synthesis of fexofenadine

Ronggeng, Wang,Yougui, Zhao,Guanchao, Zhang

, p. 2149 - 2155 (2013/06/05)

This work proposes a new simple route for fexofenadine synthesis with low cost and easily obtainable raw materials. We use benzene and methallyl as starting reactants, applying steps of Friedel-Crafts alkylation reaction, hydrolysis, oxidation, esterification reaction, and reduction reaction to obtain the intermediate product, followed by N-alkylation reaction to obtain 4-{1-hydroxy-4-[4-(hydroxydiphenyl)-piperidine]butyl}-α, α-dimethylbenzene acetate. Then, the final product fexofenadine is obtained upon hydrolysis. In the synthesis process, we constantly optimize the reaction conditions such as reaction time, reaction temperature, solvent selection, and other factors, thus improving the final yield of the target product fexofenadine to 33.51 %.

A process for producing 4-(4-halo-1-oxybutyl)-alpha,alpha-dimethylbenzene acetic acid or alkyl esters thereof

-

Page/Page column 7, (2011/04/14)

Disclosed herein is a process for large scale production of pure 4-(4-halo-1-oxybutyl)-α,α-dimethylbenzene acetic acid or alkyl esters thereof, wherein the process comprises of condensing (2-halo-1,1-dimethyl-ethyl)benzene with acetate salt followed by acylation with ω-halo compound, hydrolyzing and cyclizing the resultant regioisomers, subsequently oxidizing and purifying to obtain pure regioisomer, further halogenating and/or esterifying the para regioisomer to produce 4-(4-halo-1-oxybutyl)-α,α-dimethylbenzene acetic acid or their alkyl esters.

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