187875-33-8

Basic information

• Product Name: 1-methyl-2-(α-hydroxy-4-methoxylbenzyl)benzimidazole
• Synonyms: 1-methyl-2-(α-hydroxy-4-methoxylbenzyl)benzimidazole
• CAS NO: 187875-33-8
• Molecular Weight: 268.315
• Mol File: 187875-33-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-methyl-2-(α-hydroxy-4-methoxylbenzyl)benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-2-(α-hydroxy-4-methoxylbenzyl)benzimidazole(187875-33-8)
• EPA Substance Registry System: 1-methyl-2-(α-hydroxy-4-methoxylbenzyl)benzimidazole(187875-33-8)

Safety Data

• Hazardous Substances Data: 187875-33-8(Hazardous Substances Data)

Upstream product

• 1632-83-3 1-Methylbenzimidazole 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 59563-87-0 (4-methoxy-phenyl)-(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-methanone 
• 55326-10-8 (4-methoxyphenyl)(quinazolin-4-yl)methanone 
• 99934-03-9 7-(p-methoxybenzoyl)-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidine 
• 119-52-8 4,4'-dimethoxybenzoin 

Relevant articles and documents

Synthesis and reactivities of 1,3-dimethyl-2-(α-hydroxy-benzyl)imidazolium and 1,3-dimethyl-2-(α-hydroxybenzyl)benzimidazolium iodides

1,3-Dimethyl-2-(α-hydroxybenzyl)benzimidazolium iodide (3a) was synthesized from 1-methylbenzimidazole (10) through two steps involving lithiation and quaternization. Treatment of 3a with 4-chloro-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (6) afforded 4-benzoyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (15a). 4-Benzoylquinazoline (14a) and 7-benzoyl-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidine (16a) were given by reaction of 3a with 4-chloroquinazoline (5) and 7-chloro-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidine (7). Treatment of 3a with benzaldehyde (9a) gave benzoin (8a). Similar results were obtained in the reactions of 1,3-dimethyl-2-(α-hydroxybenzyl)imidazolium iodide (4a).