188546-71-6

Basic information

• Product Name: Benzenemethanol, a-[(diphenylphosphinyl)diethoxymethyl]-
• CAS NO: 188546-71-6
• Molecular Formula: C24H27O4P
• Molecular Weight: 410.45
• Mol File: 188546-71-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-[(diphenylphosphinyl)diethoxymethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-[(diphenylphosphinyl)diethoxymethyl]-(188546-71-6)
• EPA Substance Registry System: Benzenemethanol, a-[(diphenylphosphinyl)diethoxymethyl]-(188546-71-6)

Safety Data

• Hazardous Substances Data: 188546-71-6(Hazardous Substances Data)

Upstream product

• 122-51-0 orthoformic acid triethyl ester 
• 1079-66-9 chloro-diphenylphosphine 
• 20570-20-1 (Diethoxymethyl)diphenylphosphine oxide 
• 100-52-7 benzaldehyde 

Downstream Products

• 13049-42-8 phenylketene diethylacetal 
• 13049-42-8 C₁₂H₁₆O₂ 
• 774-40-3 hydroxy-phenyl-acetic acid ethyl ester 
• 10606-72-1 (R)-mandelic acid ethyl ester 
• 13704-09-1 (S)-(-)-ethyl mandelate 

Relevant articles and documents

Lithiated dimethoxymethyl diphenyl phosphine oxide, a versatile formiate carbanion equivalent

Aldehydes are homologated to the corresponding α-hydroxy methyl esters using lithiated dimethoxymethyl diphenyl phosphine oxide. The primary addition product of this Horner-Wittig process collapses to the corresponding α-hydroxy ester under proton-catalyzed conditions.

A New Asymmetric Formylation of Aldehydes

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