188561-56-0 Usage
General Description
METHYL 2-ACETYLAMINO-3-DIMETHYLAMINOPROPENOATE is a synthetic compound used in the production of pharmaceutical drugs and as a chemical intermediate in organic synthesis. It is a derivative of the amino acid cysteine and is often utilized in the creation of peptide molecules and other bioactive organic compounds. This chemical is commonly employed in laboratory research and drug development, and its unique structure and properties make it an important building block for the creation of various pharmaceutical products and organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 188561-56-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,5,6 and 1 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 188561-56:
(8*1)+(7*8)+(6*8)+(5*5)+(4*6)+(3*1)+(2*5)+(1*6)=180
180 % 10 = 0
So 188561-56-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H14N2O3/c1-6(11)9-7(5-10(2)3)8(12)13-4/h5H,1-4H3,(H,9,11)
188561-56-0Relevant articles and documents
Route development and multikilogram GMP delivery of a somatostatin receptor antagonist
Ruck, Rebecca T.,Huffman, Mark A.,Stewart, Gavin W.,Cleator, Ed,Kandur, Wynne V.,Kim, Mary M.,Zhao, Dalian
, p. 1329 - 1337 (2012/10/29)
Route development and demonstration on multikilogram scale for the first GMP delivery of MK-4256 are described. Key aspects of the convergent route include a regioselective green iodination, one-pot oxadiazole synthesis, and an efficient ketone Pictet-Spengler reaction with diastereomeric upgrade via crystallization to afford 6 kg of API. A recycle procedure augmented the yield of desired diastereomer in the Pictet-Spengler reaction from a mixture of diastereomers heavily enriched in the undesired diastereomer.
