188582-62-9

Basic information

• Product Name: 4-BROMO-2-FLUOROBENZYL ALCOHOL
• Synonyms: 4-BROMO-2-FLUOROBENZYL ALCOHOL;TIMTEC-BB SBB005826;RARECHEM AL BD 0386;4-BROMO-2-FLUOROBENZYL ALCOHOL 98%;4-Bromo-2-fluorobenzyl alcohol,98%;(4-Bromo-2-fluorophenyl)methanol;3-Fluoro-4-hydroxymethylbromobenzene;4-BroMo-2-fluorobenzyl alcohol, 98% 5GR
• CAS NO: 188582-62-9
• Molecular Formula: C₇H₆BrFO
• Molecular Weight: 205.02
• EINECS: -0
• Product Categories: Benzhydrols, Benzyl & Special Alcohols;Alcohol;Alcohols;Bromine Compounds;Fluorine Compounds
• Mol File: 188582-62-9.mol
• Article Data: 12

Chemical Properties

• Melting Point: 31-35 °C
• Boiling Point: 262℃
• Flash Point: 113℃
• Appearance: white to light yellow crystalline powder or chunks
• Density: 1.658
• Refractive Index: 1.5450 (estimate)
• PKA: 13.68±0.10(Predicted)
• BRN: 7757667
• CAS DataBase Reference: 4-BROMO-2-FLUOROBENZYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2-FLUOROBENZYL ALCOHOL(188582-62-9)
• EPA Substance Registry System: 4-BROMO-2-FLUOROBENZYL ALCOHOL(188582-62-9)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 24/25-26
• WGK Germany: 2
• Hazardous Substances Data: 188582-62-9(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystalline powder or chunks

Upstream product

• 57848-46-1 4-bromo-2-fluorobenzaldehyde 
• 112704-79-7 2-fluoro-4-bromobenzoic acid 
• 179232-29-2 methyl 4-bromo-2-fluorobenzoate 

Downstream Products

• 57848-46-1 4-bromo-2-fluorobenzaldehyde 
• 1514888-56-2 1-{2-fluoro-4-[5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl]-benzyl}-3-azetidine carboxylic acid 
• 134057-95-7 3-(4-bromo-2-fluorophenyl)propanoic acid 
• 881189-74-8 6-bromo-4-fluoro-2,3-dihydro-1H-inden-1-one 
• 1082066-29-2 (2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol 
• 219873-06-0 3-fluoro-4-(hydroxymethyl)benzonitrile 

Relevant articles and documents

Liquid crystal compound

PROBLEM TO BE SOLVED: To provide a compound exhibiting high dissolubility in a liquid crystal composition and high storage stability, and a liquid crystal composition and a liquid crystal display element containing the compound as a constitutional member. SOLUTION: There are provided 4-ethoxy-4'-methoxymethyl-2,3,3'-trifluorobiphenyl capable of being synthesized for example by reduction of a formyl group from 2-fluoro-4-bromobenzaldehyde, etherification and coupling with an organic boron compound like a following formula, and 4-ethoxy-4'-methoxypropyl-2,3,3'-trifluorobiphenyl capable of being synthesized by a similar method. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT

Design, synthesis, biological evaluation and in vivo testing of dual phosphodiesterase 5 (PDE5) and histone deacetylase 6 (HDAC6)-selective inhibitors for the treatment of Alzheimer's disease

We have identified chemical probes that act as dual phosphodiesterase 5 (PDE5) and histone deacetylase 6 (HDAC6)-selective inhibitors (>1 log unit difference versus class I HDACs) to decipher the contribution of HDAC isoforms to the positive impact of dua

SUBSTITUTED OXAZOLE- AND THIAZOLE-BASED CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS II

The invention relates to oxazole and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.