188614-01-9

Basic information

• Product Name: Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate
• Synonyms: Methyl-3-Oxo-3,4-Dihydro-2H-1,;Methyl 3,4-dihydro-3-oxo-2H-benzo[b][1,4]thiazine-6-carboxylate;Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate;Methyl 3,4-dihydro-3-oxo-2H-1,4-benzothiazine-6-carboxylate;methyl 3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxylate;2-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate;Methyl 3-Oxo-2H-1,4-benzothiazine-6-carboxylate;3-keto-4H-1,4-benzothiazine-6-carboxylic acid methyl ester
• CAS NO: 188614-01-9
• Molecular Formula: C₁₀H₉NO₃S
• Molecular Weight: 223.25
• Product Categories: Esters;API intermediates;Heterocycle intermediates;Fused Ring Systems
• Mol File: 188614-01-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 180-182°
• Boiling Point: 435.7 °C at 760 mmHg
• Flash Point: 217.3 °C
• Appearance: /Solid
• Density: 1.343g/cm³
• Vapor Pressure: 8.58E-08mmHg at 25°C
• Refractive Index: 1.605
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate(188614-01-9)
• EPA Substance Registry System: Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate(188614-01-9)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 188614-01-9(Hazardous Substances Data)

Usage

General Description

Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate is a chemical compound that belongs to the class of benzothiazine derivatives. It is a synthetic organic compound that is commonly used in pharmaceutical research and drug development. Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate has potential biological activities, including anti-inflammatory, anti-cancer, and anti-bacterial properties. Its structure contains a benzothiazine ring with a carboxylate ester and a methyl group, which are important for its pharmacological properties. Methyl 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylate has garnered interest in the scientific community due to its potential therapeutic applications and is actively being studied for its pharmaceutical potential.

InChI:InChI=1/C10H9NO3S/c1-14-10(13)6-2-3-8-7(4-6)11-9(12)5-15-8/h2-4H,5H2,1H3,(H,11,12)

Upstream product

• 2365-48-2 Methyl thioglycolate 
• 412947-54-7 methyl 3-amino-4-iodobenzoate 
• 188614-00-8 methyl 4-((2-ethoxy-2-oxoethyl)thio)-3-nitrobenzoate 
• 329-59-9 4-fluoro-3-nitro-benzoic acid methyl ester 
• 453-71-4 3-nitro-4-fluorobenzoic acid 

Downstream Products

• 303987-90-8 C₁₁H₁₁NO₃S 
• 272437-91-9 4-methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxylic acid 
• 226259-30-9 methyl 3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxylate 
• 1392139-44-4 C₂₃H₂₅N₃O₂S 
• 1392139-26-2 (Z)-2-benzylidene-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxylic acid 
• 272437-84-0 3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxylic acid 

Relevant articles and documents

The discovery of potent small molecule activators of human STING

The adaptor protein STING plays a major role in innate immune sensing of cytosolic nucleic acids, by triggering a robust interferon response. Despite the importance of this protein as a potential therapeutic target for serious unmet medical conditions inc

Facile synthesis of 1,4-benzothiazin-3-ones from Cu-catalyzed coupling of 2-iodoanilines and 2-mercaptoacetate

A novel synthesis of 1,4-benzothiazin-3-ones was developed from Cu-catalyzed coupling of readily available substituted 2-iodoanilines with 2-mercaptoacetate. The new method offers clear advantages over existing approaches for its one-step simple operation, wider reaction scope, and moderate to excellent isolated yields.