188790-86-5

Basic information

• Product Name: Pyrrolidine, 3-(1-ethoxyethoxy)-1-(phenylmethyl)-, (3S)-
• CAS NO: 188790-86-5
• Molecular Formula: C15H23NO2
• Molecular Weight: 249.353
• Mol File: 188790-86-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Pyrrolidine, 3-(1-ethoxyethoxy)-1-(phenylmethyl)-, (3S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolidine, 3-(1-ethoxyethoxy)-1-(phenylmethyl)-, (3S)-(188790-86-5)
• EPA Substance Registry System: Pyrrolidine, 3-(1-ethoxyethoxy)-1-(phenylmethyl)-, (3S)-(188790-86-5)

Safety Data

• Hazardous Substances Data: 188790-86-5(Hazardous Substances Data)

Upstream product

• 72229-31-3 (S)-1,2,4-butanetriol 2-(1-ethoxy-ethyl) ether 
• 76494-96-7 (2S,1'RS)-2-(1'-ethoxyethyloxy)-1,4-butanediyl bis(p-toluenesulfonate) 
• 100-46-9 benzylamine 

Downstream Products

• 118354-71-5 (S)-methanesulfonic acid 1-benzylpyrrolidin-3-yl ester 
• 101385-90-4 (S)-N-benzyl-3-hydroxypyrrolidine 

Relevant articles and documents

Preparative and structural chemistry of chiral 3-(diphenylphosphanyl)pyrrolidines and their palladium(II) complexes

The preparation of both enantiomers of 3-diphenylphosphanylpyrrolidine (2) and several N-substituted derivatives together with two Pd complexes of this ligand is reported. From L-malic acid and L-hydroxyproline both enantiomers of 3-hydroxypyrrolidine are prepared without any problems due to epimerization. KPPh2 in the presence of LiCl is shown to be the most effective reagent for the synthesis of 2. The reported X-ray structure determinations of PdI2 complexes show a rather rigid bicyclic hetero-norbornane skeleton. The flexibility of the other parts of the molecules is obvious in several polymorphs revealed by this method. This polymorphism is additionally investigated by a 31P-CP-MAS study. From solution 'H-, 13C- and 31P-NMR studies it is concluded that the bicyclic hetero-norbornane skeleton is retained in solution. VCH Verlagsgesellschaft mbH.