189028-94-2 Usage
Description
(S)-5-(4-fluorophenyl)-5-hydroxypentanoic acid is a chiral hydroxy fatty acid compound with a non-superimposable mirror image, belonging to the (S) enantiomer. It is characterized by the presence of a hydroxyl group, a pentanoic acid moiety, and a 4-fluorophenyl group, which contribute to its potential applications in various fields.
Uses
Used in Pharmaceutical Synthesis:
(S)-5-(4-fluorophenyl)-5-hydroxypentanoic acid is used as a key intermediate in the synthesis of pharmaceutical drugs for [application reason, e.g., its unique structural features that can be exploited for designing novel therapeutic agents].
Used in Organic Chemical Reactions:
In the field of organic chemistry, (S)-5-(4-fluorophenyl)-5-hydroxypentanoic acid is used as a reagent for [application reason, e.g., facilitating specific chemical transformations or reactions due to its functional groups].
Used in Pharmacology and Medicinal Chemistry Research:
(S)-5-(4-fluorophenyl)-5-hydroxypentanoic acid is used as a subject of interest in pharmacology and medicinal chemistry for [application reason, e.g., exploring its potential biological activities and its role in the development of new drugs].
Used in Chemical and Biological Research:
(S)-5-(4-fluorophenyl)-5-hydroxypentanoic acid is also used in chemical and biological research to study [application reason, e.g., its chiral properties, interactions with biological targets, or its potential as a precursor for other bioactive molecules].
Check Digit Verification of cas no
The CAS Registry Mumber 189028-94-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,9,0,2 and 8 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 189028-94:
(8*1)+(7*8)+(6*9)+(5*0)+(4*2)+(3*8)+(2*9)+(1*4)=172
172 % 10 = 2
So 189028-94-2 is a valid CAS Registry Number.
189028-94-2Relevant articles and documents
Controlling Chemoselectivity of Catalytic Hydroboration with Light
Bergamaschi, Enrico,Chen, Yi-Kai,Hohenadel, Melissa,Lunic, Danijela,McLean, Liam A.,Teskey, Christopher J.
, (2022/01/13)
The ability to selectively react one functional group in the presence of another underpins efficient reaction sequences. Despite many designer catalytic systems being reported for hydroboration reactions, which allow introduction of a functional handle fo
Iridium-Catalyzed Asymmetric Hydrogenation of ?- A nd ?-Ketoacids for Enantioselective Synthesis of ?- A nd ?-Lactones
Hua, Yun-Yu,Bin, Huai-Yu,Wei, Tao,Cheng, Hou-An,Lin, Zu-Peng,Fu, Xing-Feng,Li, Yuan-Qiang,Xie, Jian-Hua,Yan, Pu-Cha,Zhou, Qi-Lin
, p. 818 - 822 (2020/02/15)
A highly efficient asymmetric hydrogenation of ?- A nd ?-ketoacids was developed by using a chiral spiro iridium catalyst (S)-1a, affording the optically active ?- A nd ?-hydroxy acids/lactones in high yields with excellent enantioselectivities (up to >99% ee) and turnover numbers (TON up to 100000). This protocol provides an efficient and practical method for enantioselective synthesis of Ezetimibe.
METHOD OF PREPARING EZETIMIBE
-
, (2015/02/18)
A method of preparing ezetimibe. The method includes converting a compound of formula (II) to a compound of formula (III) as shown below: in which R1-R5, A1, and A2 are defined in the specification.
