18910-68-4

Basic information

• Product Name: Levalbuterol Related Compound B (20 mg) (alpha-[{(1,1-Dimethylethyl)amino}methyl]-4-hydroxy-3-methyl-benzenemethanol)
• Synonyms: Levalbuterol Related Compound B (20 mg) (alpha-[{(1,1-Dimethylethyl)amino}methyl]-4-hydroxy-3-methyl-benzenemethanol);3-Dehydroxy SalbutaMol;Levalbuterol Related CoMpound B;Salbutamol EP Impurity C;α-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-3-methyl-Benzenemethanol;4-[2-(tert-butylamino)-1-hydroxyethyl]-2-methylphenol;4-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-2-methylphenol;Levalbuterol RC B ( Salbutamol EP Impurity C)
• CAS NO: 18910-68-4
• Molecular Formula: C₁₃H₂₁NO₂
• Molecular Weight: 267.303741
• Product Categories: Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 18910-68-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 378.4±37.0 °C(Predicted)
• Appearance: /
• Density: 1.062±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 10.37±0.31(Predicted)
• CAS DataBase Reference: Levalbuterol Related Compound B (20 mg) (alpha-[{(1,1-Dimethylethyl)amino}methyl]-4-hydroxy-3-methyl-benzenemethanol)(CAS DataBase Reference)
• NIST Chemistry Reference: Levalbuterol Related Compound B (20 mg) (alpha-[{(1,1-Dimethylethyl)amino}methyl]-4-hydroxy-3-methyl-benzenemethanol)(18910-68-4)
• EPA Substance Registry System: Levalbuterol Related Compound B (20 mg) (alpha-[{(1,1-Dimethylethyl)amino}methyl]-4-hydroxy-3-methyl-benzenemethanol)(18910-68-4)

Safety Data

• Hazardous Substances Data: 18910-68-4(Hazardous Substances Data)

Usage

Description

Levalbuterol Related Compound B (20 mg) (alpha-[(1,1-Dimethylethyl)aminomethyl]-4-hydroxy-3-methyl-benzenemethanol) is a chemical compound derived from the parent drug Levalbuterol, which is a selective stimulant of β-adrenergic receptors in bronchial muscles. It is used as an impurity reference standard for the quality control of pharmaceutical products and is also known as 3-Dehydroxy Salbutamol (Levalbuterol USP Related Compound B; Salbutamol EP Impurity C).

Uses

Used in Pharmaceutical Quality Control:
Levalbuterol Related Compound B (20 mg) (alpha-[(1,1-Dimethylethyl)aminomethyl]-4-hydroxy-3-methyl-benzenemethanol) is used as an impurity reference standard for the quality control of pharmaceutical products, specifically for Levalbuterol, which is a medication used in the treatment of asthma and other respiratory conditions. Its application ensures the safety, efficacy, and purity of the final drug product.
Used in Research and Development:
In the field of pharmaceutical research and development, Levalbuterol Related Compound B (20 mg) (alpha-[(1,1-Dimethylethyl)aminomethyl]-4-hydroxy-3-methyl-benzenemethanol) serves as a valuable reference compound for the synthesis, characterization, and optimization of new drugs targeting β-adrenergic receptors. Its use in research helps in understanding the structure-activity relationship of these receptors and contributes to the development of more effective and safer medications for respiratory diseases.
Used in Regulatory Compliance:
Levalbuterol Related Compound B (20 mg) (alpha-[(1,1-Dimethylethyl)aminomethyl]-4-hydroxy-3-methyl-benzenemethanol) is also utilized in the regulatory compliance process for pharmaceutical manufacturers. It helps in meeting the regulatory requirements for drug quality, safety, and efficacy, ensuring that the final drug product meets the necessary standards before being released to the market.

Upstream product

• 24085-07-2 3'-acetoxymethyl-4'-acetoxy-2-bromoacetophenone 
• 60853-66-9 2-tert-Butylamino-1-(4-hydroxy-3-methyl-phenyl)-ethanone 
• 41877-17-2 2-bromo-1-(4-hydroxy-3-methylphenyl)ethan-1-one 
• 876-02-8 4-hydroxy-3-methylphenyl methyl ketone 
• 24085-03-8 α-[(benzyl-tert-butylamino)methyl]-m-xylene-4,α,α'-triol 

Relevant articles and documents

Preparation method and application of salbutamol impurity

The invention discloses a preparation method and application of a salbutamol impurity. The preparation method adopts the following process route of taking 2-acetoxy-5-(2-bromoacetyl) benzyl acetate (ABBA) as an initial raw material, and firstly reacting w

Saligenin analogs of sympathomimetic catecholamines.

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