189163-46-0

Basic information

• Product Name: 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-(diphenylmethyl) ester, (2R,4R)-
• CAS NO: 189163-46-0
• Molecular Formula: C23H27NO5
• Molecular Weight: 397.471
• Mol File: 189163-46-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-(diphenylmethyl) ester, (2R,4R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-(diphenylmethyl) ester, (2R,4R)-(189163-46-0)
• EPA Substance Registry System: 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-(diphenylmethyl) ester, (2R,4R)-(189163-46-0)

Safety Data

• Hazardous Substances Data: 189163-46-0(Hazardous Substances Data)

Upstream product

• 135042-12-5 (4R)-1-(tert-butoxycarbonyl)-4-hydroxy-D-proline 
• 908093-98-1 diazodiphenylmethane 

Downstream Products

• 189163-79-9 (2R,4S)-4-Formyloxy-pyrrolidine-1,2-dicarboxylic acid 2-benzhydryl ester 1-tert-butyl ester 
• 1257225-15-2 N-(tert-butoxycarbonyl)-(4'R)-p-toluenesulfonyloxy-(2'R)-proline diphenylmethyl ester 
• 1558041-17-0 (2R,4S)-2-benzhydryl 1-tert-butyl 4-(3-ethyl-1-methyl-1H-pyrazole-5-carboxamido)pyrrolidine-1,2-dicarboxylate 
• 1558041-16-9 (2R,4S)-2-benzhydryl 1-tert-butyl 4-aminopyrrolidine-1,2-dicarboxylate 
• 1558041-15-8 1-(1,1-dimethylethyl) 2-(diphenylmethyl) (2R,4S)-4-azido-1,2-pyrrolidinedicarboxylate 
• 189163-50-6 (2R,4R)-4-(3-Benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-pyrrolidine-1,2-dicarboxylic acid 2-benzhydryl ester 1-tert-butyl ester 
• 189163-59-5 (2R,4R)-4-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-pyrrolidine-1,2-dicarboxylic acid 2-benzhydryl ester 1-tert-butyl ester 
• 189163-47-1 N-tert-butoxycarbonyl-trans-4-hydroxy-D-proline diphenylmethyl ester 
• 189163-53-9 (2R,4S)-4-(3-Benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-1-[2-(9H-fluoren-9-ylmethoxycarbonylamino)-acetyl]-pyrrolidine-2-carboxylic acid benzhydryl ester 
• 189163-54-0 (2R,4R)-4-(3-Benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-1-[2-(9H-fluoren-9-ylmethoxycarbonylamino)-acetyl]-pyrrolidine-2-carboxylic acid benzhydryl ester 
• 189163-63-1 (2R,4R)-1-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)-acetyl]-4-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-pyrrolidine-2-carboxylic acid benzhydryl ester 
• 189163-57-3 (2R,4R)-4-(6-Benzoylamino-purin-9-yl)-1-[2-(9H-fluoren-9-ylmethoxycarbonylamino)-acetyl]-pyrrolidine-2-carboxylic acid benzhydryl ester 
• 189163-60-8 (2R,4R)-4-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-1-[2-(9H-fluoren-9-ylmethoxycarbonylamino)-acetyl]-pyrrolidine-2-carboxylic acid benzhydryl ester 
• 189163-82-4 (2R,4R)-4-{2-Isobutyrylamino-6-[2-(4-nitro-phenyl)-ethoxy]-purin-9-yl}-pyrrolidine-1,2-dicarboxylic acid 2-benzhydryl ester 1-tert-butyl ester 

Relevant articles and documents

Dipeptides bearing nucleobases for the synthesis of novel peptide nucleic acids

Three stereoisomers (cis-L, trans-D and cis-D) of N-Fmoc-glycyl-4-(thymin-1-y)proline and their pentafluorophenyl esters have been prepared for use in the synthesis of novel peptide nucleic acids. In addition, N-Fmoc-glycyl-4-(N6-benzoyladenin-9-yl)proline, N-Fmoc-glycyl-4-(N4-benzoylcytosin-1-yl)proline and N-Fmoc-glycyl-4-(N2-isobutyrylguanin-9-yl)proline and their pentafluorophenyl esters of the cis-D series have been synthesized.