191673-76-4

Basic information

• Product Name: methyl 3-(3,4-dichlorophenyl)-3-butenoate
• Synonyms: methyl 3-(3,4-dichlorophenyl)-3-butenoate
• CAS NO: 191673-76-4
• Molecular Weight: 245.105
• Mol File: 191673-76-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 3-(3,4-dichlorophenyl)-3-butenoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(3,4-dichlorophenyl)-3-butenoate(191673-76-4)
• EPA Substance Registry System: methyl 3-(3,4-dichlorophenyl)-3-butenoate(191673-76-4)

Safety Data

• Hazardous Substances Data: 191673-76-4(Hazardous Substances Data)

Upstream product

• 18282-59-2 4-bromo-1,2-dichlorobenzene 
• 67-56-1 methanol 
• 1034183-25-9 3-(3,4-Dichloro-phenyl)-but-3-enoic acid 

Downstream Products

• 191673-50-4 [(R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-(3,4-dichloro-phenyl)-2-hydroxy-butyl]-(2-hydroxy-ethyl)-carbamic acid tert-butyl ester 
• 191673-60-6 2-[4-t-Butoxycarbonyl-(2 R)-(3,4-dichlorophenyl)morpholin-2-yl]ethanol t-butyldimethylsilyl ether 
• 191673-32-2 (R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-(3,4-dichloro-phenyl)-butane-1,2-diol 
• 191673-56-0 (R)-2-(2-(3,4-dichlorophenyl)morpholin-2-yl)ethanol 
• 191673-30-0 tert-Butyl-[3-(3,4-dichloro-phenyl)-but-3-enyloxy]-dimethyl-silane 
• 272775-65-2 3-(3',4'-dichlorophenyl)-3-buten-1-ol 

Relevant articles and documents

Salts of an optically-active sulfoxide derivative

Hydrochloride of fumarate of 1-{2-[(2R)-(3,4-dichlorophenyl)-4-(3,4,5-trimethyoxybenzoyl)morpholin-2-yl]ethyl}spiro[benzo(c)thiophene-1(3H),4′-piperidin]-(2S)-oxide. These compounds have good oral adsorption and exhibit markedly excellent antagonistic act

An efficient synthesis of enantiomerically pure 2-[(2R)-arylmorpholin- 2-yl]ethanols, key intermediates of tachykinin receptor antagonist

We report herein an efficient and practical synthetic method for the preparation of enantiomerically pure 2[(2R)-arylmorpholin-2-yl]ethanols 1a- d, key intermediates of tachykinin receptor antagonist. Sharpless catalytic asymmetric dihydroxylation of 4a-d was employed to introduce the required absolute stereochemistry, and cyclization of 7a-d was accomplished by the Mitsunobu reaction.