1928-39-8

Basic information

• Product Name: ethyl 2,4,5-trichlorophenoxyacetate
• Synonyms: ethyl 2,4,5-trichlorophenoxyacetate;2,4,5-Trichlorophenoxyacetic acid ethyl ester
• CAS NO: 1928-39-8
• Molecular Formula: C₁₀H₉Cl₃O₃
• Molecular Weight: 283.53566
• EINECS: 217-671-2
• Mol File: 1928-39-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 334.88°C (rough estimate)
• Flash Point: 138.6°C
• Appearance: /
• Density: 1.401g/cm³
• Vapor Pressure: 6.92E-05mmHg at 25°C
• Refractive Index: 1.538
• CAS DataBase Reference: ethyl 2,4,5-trichlorophenoxyacetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2,4,5-trichlorophenoxyacetate(1928-39-8)
• EPA Substance Registry System: ethyl 2,4,5-trichlorophenoxyacetate(1928-39-8)

Safety Data

• Hazardous Substances Data: 1928-39-8(Hazardous Substances Data)

Usage

General Description

Ethyl 2,4,5-trichlorophenoxyacetate, also known as 2,4,5-T, is a synthetic organic compound that belongs to the class of chlorophenoxy herbicides. It is derived from trichlorophenol and acetic acid, and is commonly used to control broadleaf weeds in crops such as maize, rice, and wheat. 2,4,5-T has been banned in many countries due to its toxic effects on humans and the environment. It has been linked to several health issues, including cancer, reproductive problems, and skin and eye irritation. Additionally, exposure to 2,4,5-T has been associated with environmental concerns such as groundwater contamination and harmful effects on non-target organisms.

InChI:InChI=1/C10H9Cl3O3/c1-2-15-10(14)5-16-9-4-7(12)6(11)3-8(9)13/h3-4H,2,5H2,1H3

Upstream product

• 95-95-4 2,4,5-trichlorophenol 
• 105-36-2 ethyl bromoacetate 
• 64-67-5 diethyl sulfate 
• 93-76-5 2,4,5-Trichlorophenoxyacetic acid 
• 61763-88-0 (2,5-dichloro-phenoxy)-acetic acid ethyl ester 
• 64-17-5 ethanol 
• 777-08-2 2-(2,4,5-trichlorophenoxy)acetyl chloride 

Downstream Products

• 2381-77-3 2,4,5-trichloro-phenoxyacetic acid hydrazide 
• 14722-47-5 2,4,5-Trichlor-phenoxy-acethydroxamsaeure 

Relevant articles and documents

Expedient discovery for novel antifungal leads: 1,3,4-Oxadiazole derivatives bearing a quinazolin-4(3H)-one fragment

Developing novel fungicide candidates are intensively promoted by the rapid emergences of resistant fungi that outbreak on agricultural production. Aiming to discovery novel antifungal leads, a series of 1,3,4-oxadiazole derivatives bearing a quinazolin-4(3H)-one fragment were constructed for evaluating their inhibition effects against phytopathogenic fungi in vitro and in vivo. Systematically structural optimizations generated the bioactive molecule I32 that was identified as a promising inhibitor against Rhizoctonia solani with the in vivo preventative effect of 58.63% at 200 μg/mL. The observations that were captured by scanning electron microscopy and transmission electron microscopy demonstrated that the bioactive molecule I32 could induce the sprawling growth of hyphae, the local shrinkage and rupture on hyphal surfaces, the extreme swelling of vacuoles, the striking distortions on cell walls, and the reduction of mitochondria numbers. The above results provided an indispensable complement for the discovery of antifungal lead bearing a quinazolin-4(3H)-one and 1,3,4-oxadiazole fragment.