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192927-63-2

192927-63-2

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192927-63-2 Usage

Chemical Properties

Crystalline Solid

Uses

Different sources of media describe the Uses of 192927-63-2 differently. You can refer to the following data:
1. A fluorinated quinolone antibacterial
2. A fluorinated quinolone antibacterial.

Check Digit Verification of cas no

The CAS Registry Mumber 192927-63-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,2,9,2 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 192927-63:
(8*1)+(7*9)+(6*2)+(5*9)+(4*2)+(3*7)+(2*6)+(1*3)=172
172 % 10 = 2
So 192927-63-2 is a valid CAS Registry Number.
InChI:InChI=1/C21H24FN3O4.ClH.H2O/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24;;/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28);1H;1H2/t11-,16+;;/m0../s1

192927-63-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid,hydrate,hydrochloride

1.2 Other means of identification

Product number -
Other names Actira

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:192927-63-2 SDS

192927-63-2Synthetic route

L(+)-moxifloxacin tartrate
1082245-30-4

L(+)-moxifloxacin tartrate

1-cyclopropyl-7-([S,S]-2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid monohydrochloride monohydrate
192927-63-2

1-cyclopropyl-7-([S,S]-2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid monohydrochloride monohydrate

Conditions
ConditionsYield
With hydrogenchloride; water In ethanol at 25 - 30℃; for 1h; Product distribution / selectivity;85%
1-cyclopropyl-7-[(S,S)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid fumarate
1082245-33-7

1-cyclopropyl-7-[(S,S)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid fumarate

1-cyclopropyl-7-([S,S]-2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid monohydrochloride monohydrate
192927-63-2

1-cyclopropyl-7-([S,S]-2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid monohydrochloride monohydrate

Conditions
ConditionsYield
With hydrogenchloride; water In ethanol at 25 - 30℃; for 1h; Product distribution / selectivity;81.82%
1-cyclopropyl-7-[(S,S)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid di-p-toluoyl-L-tartarate
1082245-36-0

1-cyclopropyl-7-[(S,S)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid di-p-toluoyl-L-tartarate

1-cyclopropyl-7-([S,S]-2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid monohydrochloride monohydrate
192927-63-2

1-cyclopropyl-7-([S,S]-2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid monohydrochloride monohydrate

Conditions
ConditionsYield
With hydrogenchloride; water In ethanol at 25 - 30℃; for 1h; Product distribution / selectivity;69.2%
1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
112811-72-0

1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid

(1S,6S)-2,8-diazabicyclo[4.3.0]nonane
151213-40-0

(1S,6S)-2,8-diazabicyclo[4.3.0]nonane

1-cyclopropyl-7-([S,S]-2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid monohydrochloride monohydrate
192927-63-2

1-cyclopropyl-7-([S,S]-2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid monohydrochloride monohydrate

Conditions
ConditionsYield
Stage #1: 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid With boric acid; acetic anhydride; zinc(II) chloride at 25 - 120℃; for 1.5h;
Stage #2: (1S,6S)-2,8-diazabicyclo[4.3.0]nonane With triethylamine In acetonitrile for 1.5h; Heating / reflux;
Stage #3: With hydrogenchloride; sodium hydroxide; water; acetic acid more than 3 stages;
1-cyclopropyl-7-([S,S]-2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid monohydrochloride monohydrate
192927-63-2

1-cyclopropyl-7-([S,S]-2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid monohydrochloride monohydrate

moxifloxacin hydrochloride
186826-86-8

moxifloxacin hydrochloride

Conditions
ConditionsYield
In toluene Heating / reflux;

192927-63-2Downstream Products

192927-63-2Relevant articles and documents

Process for the preparation of moxifloxacin hydrochloride

-

Page/Page column 11-12, (2008/12/09)

The present invention relates to a process for the preparation of Moxifloxacin hydrochloride monohydrate, of the formula

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