193085-24-4

Basic information

• Product Name: 1-BOC-PIPERIDIN-4-YLIDENE-ACETIC ACID
• Synonyms: 1-BOC-4-CARBOXYMETHYLENE-PIPERIDINE;1-BOC-PIPERIDIN-4-YLIDENE-ACETIC ACID;4-CARBOXYMETHYLENE-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-Boc-piperidin-4-ylidene avetic acid;1-Boc-Piperidin-4-ylidene-acetic acid N-Boc-Piperidin-4-ylidene-acetic acid 2-(1-(tert-butoxycarbonyl)piperidin-4-ylidene)acetic acid;1-N-Boc-Piperidin-4-ylidene-acetic acid;2-(1-Boc-piperidin-4-ylidene)acetic acid;(1-Boc-4-piperidinylidene)acetic acid
• CAS NO: 193085-24-4
• Molecular Formula: C₁₂H₁₉NO₄
• Molecular Weight: 241.28
• Mol File: 193085-24-4.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 386.951 °C at 760 mmHg
• Flash Point: 187.822 °C
• Appearance: /
• Density: 1.228 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.564
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-BOC-PIPERIDIN-4-YLIDENE-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BOC-PIPERIDIN-4-YLIDENE-ACETIC ACID(193085-24-4)
• EPA Substance Registry System: 1-BOC-PIPERIDIN-4-YLIDENE-ACETIC ACID(193085-24-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-36
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 193085-24-4(Hazardous Substances Data)

Usage

General Description

1-BOC-PIPERIDIN-4-YLIDENE-ACETIC ACID is a chemical compound with a molecular formula C13H19NO4. It is a derivative of piperidine and is commonly used in organic synthesis as a building block for various pharmaceuticals and agrochemicals. The presence of the BOC (tert-butyloxycarbonyl) protecting group allows for selective reactions and manipulation of the molecule's structure. 1-BOC-PIPERIDIN-4-YLIDENE-ACETIC ACID is of interest in drug discovery and development due to its potential pharmacological properties and its ability to be modified into various derivatives for medicinal applications. Additionally, 1-BOC-PIPERIDIN-4-YLIDENE-ACETIC ACID is a valuable intermediate in the production of other organic compounds used in the pharmaceutical and agricultural industries.

InChI:InChI=1/C12H19NO4/c1-12(2,3)17-11(16)13-6-4-9(5-7-13)8-10(14)15/h8H,4-7H2,1-3H3,(H,14,15)

Upstream product

• 84839-55-4 tert.butyl 1-tert.butyloxycarbonyl-Δ^4,α-piperidineacetate 
• 169206-65-9 1-tert-butoxycarbonyl-4-[(methoxycarbonyl)methylene]piperidine 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 41979-39-9 4-piperidone hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 135716-08-4 tert-butyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate 

Downstream Products

• 193085-25-5 4-[(methyl-{1-[methyl-(1-methylcarbamoyl-2-phenyl-ethyl)-carbamoyl]-2-naphthalen-2-yl-ethyl}-carbamoyl)-methylene]-piperidine-1-carboxylic acid tert-butyl ester 
• 1351940-60-7 tert-butyl 4-(2-(4-(3-chloro-4-(pyridin-2-yl-methoxy)phenylamino)-3-cyano-7-(tetrahydrofuran-3-yl-oxy)quinolin-6-yl-amino)-2-oxoethylidene)piperidine-1-carboxylate 
• 1426946-00-0 C₂₂H₃₀N₂O₆ 
• 1426946-06-6 C₂₁H₂₈N₄O₃S 
• 1426946-05-5 C₂₁H₂₇ClN₄O₃S 
• 1426946-02-2 C₂₃H₂₈N₄O₃ 
• 1381841-45-7 C₂₀H₂₀ClN₃ 
• 151238-69-6 C₂₀H₂₀FN₃ 
• 1005195-59-4 N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)quinazolin-6-yl)-2-(piperidin-4-ylidene)acetamide trifluoroacetate 
• 1005195-58-3 N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)quinazolin-6-yl)-2-(piperidin-4-ylidene)acetamide 
• 1005194-71-7 N-(4-(3-ethynylphenylamino)quinazolin-6-yl)-2-(1-methylpiperidin-4-ylidene)acetamide 
• 1005194-69-3 N-(4-(3-ethynylphenylamino)quinazolin-6-yl)-2-(piperidin-4-ylidene)acetamide 
• 1005195-57-2 tert-butyl 4-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino) quinazolin-6-ylamino)-2-oxoethylidene) piperidine-1-carboxylate 
• 1005194-68-2 tert-butyl 4-(2-(4-(3-ethynylphenylamino)quinazolin-6-ylamino)-2-oxoethylidene)piperidine-1-carboxylate 

Relevant articles and documents

GLP-1R AGONISTS AND USES THEREOF

Provided herein are compounds of Formula (I) and pharmaceutical compositions thereof, for use in, e.g. treating type 2 diabetes mellitus, pre-diabetes, obesity, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, and cardiovascular disease.

QUINAZOLINE AND QUINOLINE DERIVATIVES AS IRREVERSIBLE PROTEIN TYROSINE KINASE INHIBITORS

A compound of formula (I), a pharmaceutically acceptable salt, or hydrate thereof, and a method of preparing the same. A method of treating or preventing a physiological disorder caused by abnormal protein tyrosine kinase activity in a mammal comprising administering to said mammal a pharmaceutical composition comprising a compound of formula (I).

BENZOFURAN DERIVATIVE

The present invention provides a benzofuran derivative of the formula [1]: wherein x is a group of the formula: -N="or" -CH=; Y is an optionally substituted amino group, an optionally substituted cycloalkyl group or an optionally substituted saturated heterocyclic group; A is a single bond, a carbon chain optionally having a double bond within or at the end(s) of the chain, or an oxygen atom; R1 is a hydrogen atom or a halogen atom; Ring B is an optionally substituted benzene ring; and R3 is a hydrogen atom, or a pharmaceutically acceptable salt thereof, which is useful as a medicament, especially as an activated blood coagulation factor X inhibitor.