193953-12-7

Basic information

• Product Name: (R)-3-(tert-Butyl-diphenyl-silanyloxy)-butyric acid (R)-2-{(R)-2-[(R)-2-(9H-fluoren-9-ylmethoxycarbonyl)-1-methyl-ethoxycarbonyl]-1-methyl-ethoxycarbonyl}-1-methyl-ethyl ester
• CAS NO: 193953-12-7
• Molecular Weight: 779.015
• Mol File: 193953-12-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-(tert-Butyl-diphenyl-silanyloxy)-butyric acid (R)-2-{(R)-2-[(R)-2-(9H-fluoren-9-ylmethoxycarbonyl)-1-methyl-ethoxycarbonyl]-1-methyl-ethoxycarbonyl}-1-methyl-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-(tert-Butyl-diphenyl-silanyloxy)-butyric acid (R)-2-{(R)-2-[(R)-2-(9H-fluoren-9-ylmethoxycarbonyl)-1-methyl-ethoxycarbonyl]-1-methyl-ethoxycarbonyl}-1-methyl-ethyl ester(193953-12-7)
• EPA Substance Registry System: (R)-3-(tert-Butyl-diphenyl-silanyloxy)-butyric acid (R)-2-{(R)-2-[(R)-2-(9H-fluoren-9-ylmethoxycarbonyl)-1-methyl-ethoxycarbonyl]-1-methyl-ethoxycarbonyl}-1-methyl-ethyl ester(193953-12-7)

Safety Data

• Hazardous Substances Data: 193953-12-7(Hazardous Substances Data)

Upstream product

• 178246-83-8 (R)-3-(tert-Butyl-diphenyl-silanyloxy)-butyric acid (R)-2-[(R)-2-((R)-2-carboxy-1-methyl-ethoxycarbonyl)-1-methyl-ethoxycarbonyl]-1-methyl-ethyl ester 
• 24324-17-2 9-Fluorenylmethanol 

Downstream Products

• 193953-30-9 3,5-Bis-(tert-butyl-diphenyl-silanyloxymethyl)-benzoic acid (R)-2-((R)-2-{(R)-2-[(R)-2-(9H-fluoren-9-ylmethoxycarbonyl)-1-methyl-ethoxycarbonyl]-1-methyl-ethoxycarbonyl}-1-methyl-ethoxycarbonyl)-1-methyl-ethyl ester 
• 193953-33-2 3,5-Bis-hydroxymethyl-benzoic acid (R)-2-((R)-2-{(R)-2-[(R)-2-(9H-fluoren-9-ylmethoxycarbonyl)-1-methyl-ethoxycarbonyl]-1-methyl-ethoxycarbonyl}-1-methyl-ethoxycarbonyl)-1-methyl-ethyl ester 

Relevant articles and documents

76. Synthesis of Monodisperse Macromolecular Bicyclic and Dendritic Compounds from (R)-3-Hydroxybutanoic Acid and Benzene-1,3,5-tricarboxylic Acid and Analysis by Fragmenting MALDI-TOF Mass Spectroscopy

As previously shown, oligo- and poly(β-hydroxyalkanoates) have a high tendency to form lamellar crystallites with ca. 50-A thickness which corresponds to chain lengths of 16 units (Fig. 1). To have monodisperse model compounds, we have now prepared bicyclic derivatives with three parallel (27-29) or two parallel and an antiparallel chain (68-70) consisting of up to 16 3-hydroxybutanoate (3-HB) units. We also prepared dendritic compounds (71-75, 82-85) containing oligo(3-HB) chains which cannot possibly he arranged as in the lamellae; the branching units were prepared from trimesic acid (= benzene-1,3,5-tricarboxylic acid). So far, none of the prepared samples formed crystals or contained crystalline domains which would have been suitable for single-crystal or powder-diffraction X-ray analysis. The terminally deprotected dendrimers (74, 75, and 85) are multi-anionic (up to 12 peripheral CO2H groups) and biodegradable. The macromolecular HB derivatives (molecular weight up to 10150 Da) have been fully characterized by IR, 1H- and 13C-NMR, [α]D, and elemental analysis. Especially important is the analysis by mass spectrometry with the MALDI-TOF technique (Fig. 2), proving that the products are monodisperse; application of a new variation of this MS method (post source decay = PSD or fragment analysis by structural time of night = FAST) allows for the observation of metastable fragment ions and, thus, is a tool for structural oligomer analysis (Fig. 3).