1940-43-8

Basic information

• Product Name: TETRACHLOROPHENE
• Synonyms: 2,2’-methylenebis(4,6-dichloro-pheno;2,2’-methylenebis(4,6-dichlorophenol);bis(2-hydroxy-3,5-dichlorophenyl)methane;TETRACHLOROPHENE;6,6'-Methylenebis(2,4-dichlorophenol)
• CAS NO: 1940-43-8
• Molecular Formula: C₁₃H₈Cl₄O₂
• Molecular Weight: 338.01
• EINECS: 217-720-8
• Mol File: 1940-43-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 430.8°Cat760mmHg
• Flash Point: 214.3°C
• Appearance: /
• Density: 1.583g/cm³
• PKA: pK1:5.6;pK2:10.56 (25°C)
• CAS DataBase Reference: TETRACHLOROPHENE(CAS DataBase Reference)
• NIST Chemistry Reference: TETRACHLOROPHENE(1940-43-8)
• EPA Substance Registry System: TETRACHLOROPHENE(1940-43-8)

Safety Data

• Hazardous Substances Data: 1940-43-8(Hazardous Substances Data)

Usage

General Description

Tetrachlorophene is a chlorinated bisphenol antiseptic and disinfectant that is commonly used in soaps and surgical scrubs. It is effective against a variety of bacteria and some fungi, making it useful in preventing and treating skin infections. However, tetrachlorophene can be toxic if ingested or absorbed through the skin in large amounts, and it has been associated with adverse effects on the central nervous system and liver. Due to these potential risks, tetrachlorophene is regulated in many countries, and its use is limited to certain medical and veterinary applications.

Upstream product

• 50-00-0 formaldehyd 
• 120-83-2 2,4-dichlorophenol 
• 6641-02-7 3,5-dichloro-2-hydroxybenzyl alcohol 
• 2467-02-9 Bis(2-hydroxyphenyl)methane 
• 7664-93-9 sulfuric acid 
• 64-19-7 acetic acid 
• 855156-83-1 bis-(3,5-dichloro-2-hydroxy-benzyl)-ether 
• 100-97-0 hexamethylenetetramine 

Downstream Products

• 7507-67-7 bis-(2-acetoxy-3,5-dichloro-phenyl)-methane 
• 945538-96-5 (3,5-dichloro-2-hydroxyphenyl)(3,5-dichloro-2-hydroxyethoxyphenyl)methane 
• 945538-94-3 bis(3,5-dichloro-2-hydroxyethoxyphenyl)methane 
• 114508-88-2 2,2'-Dihydroxy-3,5,3',5'-tetrachlor-diphenylmethan-bis-(2,4-dinitrophenyl)-ether 
• 99711-21-4 3,3',5,5'-Tetrachlor-2,2'-bis-(2,3-dihydroxy-propoxy)-diphenylmethan 
• 107919-79-9 bis-(3,5-dichloro-2-methoxy-phenyl)-methane 

Relevant articles and documents

One-step novel synthesis of methylene bisphenols and methylene bisnaphthols using Lewis acid mediated rearrangement

Mono- and di-substituted isomeric methylene bisphenols and methylene bisnaphthols have been synthesized by rearrangement of the corresponding O-methoxyacetyl derivatives of phenols and naphthols, respectively, in presence of aluminium chloride under dry conditions. The chemistry observed is different from the usual Fries rearrangement reaction and involves an intermolecular rearrangement. The reactions reported here also reflect the influence of substituents present in the substrate as is supported by the substitution of the bridging methylene at a position meta to the phenolic hydroxyl in some of the minor products formed along-side the majorly formed ortho substituted products.

Anticalculus composition

This invention relates to an improved composition for inhibiting dental plaque and calculus formation, comprising zinc ions and a non-toxic, organoleptically acceptable antibacterial agent in an orally acceptable medium, and to a process for retarding the growth of dental plaque and calculus by application to the teeth of the above composition.