194032-43-4

Basic information

• Product Name: (2S,5S)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: (2S,5S)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;(2S,5S)-1-N-BOC-2,5-DIMETHYLPIPERAZINE;(2R,5R)-1-N-BOC-2,5-DIMETHYLPIPERAZINE;(2R,5R)-1-Boc-2,5-diMethylpiperazine-HCl;(2R,5R)-tert-Butyl 2,5-diMethylpiperazine-1-carboxylate hydrochloride;(2R,5R)-2,5-Dimethyl-1-piperazinecarboxylic acid 1,1-dimethylethyl ester;(2R,5R)-rel-tert-Butyl 2,5-dimethylpiperazine-1-carboxylate
• CAS NO: 194032-43-4
• Molecular Formula: C11H22N2O2
• Molecular Weight: 214.30458
• Mol File: 194032-43-4.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 279.7℃
• Flash Point: 123.0℃
• Appearance: /
• Density: 0.970
• Vapor Pressure: 0.00394mmHg at 25°C
• Refractive Index: 1.452
• PKA: 8.55±0.60(Predicted)
• CAS DataBase Reference: (2S,5S)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,5S)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(194032-43-4)
• EPA Substance Registry System: (2S,5S)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(194032-43-4)

Safety Data

• Hazardous Substances Data: 194032-43-4(Hazardous Substances Data)

Usage

General Description

(2S,5S)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is a chemical compound with the molecular formula C13H24N2O2. It is a tert-butyl ester derivative of (2S,5S)-2,5-dimethylpiperazine-1-carboxylic acid, which is an acidic amino acid commonly used in the synthesis of peptides and pharmaceuticals. The tert-butyl ester group is often used to protect the carboxylic acid functionality and facilitate its incorporation into larger molecules. (2S,5S)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER may be used as an intermediate in organic synthesis or as a building block in the preparation of pharmaceutical compounds.

InChI:InChI=1/C11H22N2O2/c1-8-7-13(9(2)6-12-8)10(14)15-11(3,4)5/h8-9,12H,6-7H2,1-5H3/t8-,9-/m0/s1

Upstream product

• 548762-65-8 (2R,5S)-1-benzyloxycarbonyl-4-tert-butoxycarbonyl-2,5-dimethylpiperazine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 155836-79-6 (+)-(2S,5R)-1-allyl-2,5-dimethylpiperazine 
• 2815-34-1 2,5-dimethyl-piperazine 
• 548762-64-7 (2R,5S)-1-benzyloxycarbonyl-2,5-dimethylpiperazine 
• 548762-58-9 (2S,5R)-1-allyl-4-benzyloxycarbonyl-2,5-dimethylpiperazine 
• 431062-01-0 4-(4-fluoro-benzyl)-2R,5S-dimethyl-piperazine-1-carboxylic acid tert-butyl ester 
• 106-55-8 2,5-dimethylpiperazine 
• 1218941-14-0 C₁₈H₂₇FN₂O₂ 
• 1238951-64-8 C₁₄H₂₆N₂O₂ 
• 431062-00-9 4-benzyl-2R,5S-dimethyl-piperazine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 155836-78-5 (-)-(2R,5S)-1-allyl-2,5-dimethylpiperazine 

Relevant articles and documents

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Provided are opioid receptor antagonists represented by the formula (I) where R, Y3, R1, R2, R3, R4 and R5 are as defined herein.

CARBINOL DERIVATIVES HAVING HETEROCYCLIC LINKER

[Object] It is to provide a novel LXRβ agonist useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia; hypercholesterolemia; lipid-related diseases; inflammatory diseases that are caused by inflammatory cytokines; skin diseases such as allergic skin diseases; diabetes; or Alzheimer's disease. [Solving Means] A carbinol compound represented by the following general formula (I) or salt thereof, or their solvate: (wherein, each V and W independently show N or C—R7; each X and Y independently show CH2, C═O, SO2, etc; Z shows CH or N; each R1, R2 and R7 independently show a hydrogen atom, C1-8 alkyl group, etc.; R3 shows C1-8 alkyl group; R4 shows an optionally substituted C6-10 aryl group or an optionally substituted 5- to 11-membered heterocyclic group; R5 and R6 show a hydrogen atom, etc.; L shows a C1-8 alkyl chain optionally substituted with an oxo group, etc.; and n shows any integer of 0 to 2.)