194228-60-9 Usage
Heterocyclic organic compound
It contains both carbon and nitrogen atoms in its ring structure, making it a heterocyclic compound.
Chlorine and iodine atoms
The compound has three chlorine atoms at the 2nd, 6th, and 7th positions, and one iodine atom at the 3rd position.
Unique structure and properties
The presence of both chlorine and iodine atoms in the imidazo[1,2-a]pyridine ring gives this compound its unique structure and properties.
Potential applications in pharmaceuticals and agrochemicals
Due to its unique structure and properties, this compound can be used in the development of new drugs and agrochemicals.
Synthesis of biologically active compounds
2,6,7-trichloro-3-iodoimidazo[1,2-a]pyridine can be used as a building block in the synthesis of various biologically active compounds.
Intermediate in chemical production
This compound can also serve as an intermediate in the production of other chemicals, further expanding its potential applications.
Handling precautions
It is important to handle 2,6,7-trichloro-3-iodoimidazo[1,2-a]pyridine with care, as it may pose risks to health and safety if not properly managed.
Check Digit Verification of cas no
The CAS Registry Mumber 194228-60-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,2,2 and 8 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 194228-60:
(8*1)+(7*9)+(6*4)+(5*2)+(4*2)+(3*8)+(2*6)+(1*0)=149
149 % 10 = 9
So 194228-60-9 is a valid CAS Registry Number.
194228-60-9Relevant articles and documents
Synthesis and antiviral activity of novel erythrofuranosyl imidazo[1,2-α]pyridine C-nucleosides constructed via palladium coupling of iodoimidazo[1,2-α]pyridines and dihydrofuran
Gudmundsson, Kristjan S.,Williams, John D.,Drach, John C.,Townsend, Leroy B.
, p. 1449 - 1455 (2003)
2,5,6-Trichloro-1-(β-D-ribofuranosyl)benzimidazole (TCRB) and certain analogues have shown significant activity against human cytomegalovirus. The metabolic instability of the glycosidic linkage in TCRB prompted us to synthesize the structurally similar imidazo[1,2-α]pyridine erythrofuranosyl C-nucleosides. As an approach to the synthesis of polychlorinated imidazo-[1,2-α]pyridine C-3-erythrofuranosides, a palladium-based methodology for coupling 2,3-dihydrofuran with chlorinated 3-iodoimidazo[1,2-α]pyridines was developed and optimized to give 80-90% yields of 2,6-dichloro- and 2,6,7-trichloro-3-(2,3-dideoxy-2,3-didehydro-D/L-erythrofuranosyl)- imidazo[1,2-α]pyridine. Dihydroxylation of these didehydro derivatives with osmium tetroxide or with AD-mix α gave a mixture of erythrofuranosyl C-nucleosides that were separated by standard and then chiral chromatography. When screened for anti-HCMV and HSV-1 activity, the α-D anomer of 2,6,7-trichloro-3-(erythrofuranosyl)imidazo[1,2-a]pyridine proved to be the most active member of the series, while the α-anomers all proved to be inactive.
