19447-73-5 Usage
Structure
Contains a purine derivative with a thiocyanate group attached to the 6th position of the purine ring.
Thiocyanate Group
A chemical group (-SCN) consisting of sulfur, carbon, and nitrogen atoms bonded in a linear arrangement. Thiocyanates exhibit diverse chemical and biological properties.
Purine Moiety
The presence of a purine ring suggests potential pharmacological activity due to the involvement of purines in various drugs targeting medical conditions like cancer, viral infections, and inflammatory diseases.
Biological and Chemical Properties
Thiocyanates are known for their diverse properties, both biological and chemical, making them useful in industrial and pharmaceutical applications.
Potential Applications
The compound may have potential applications in pharmaceuticals, possibly for medicinal purposes due to the purine moiety, but further research is required to determine its specific properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 19447-73-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,4,4 and 7 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 19447-73:
(7*1)+(6*9)+(5*4)+(4*4)+(3*7)+(2*7)+(1*3)=135
135 % 10 = 5
So 19447-73-5 is a valid CAS Registry Number.
19447-73-5Relevant articles and documents
Synthesis of some novel thiocyanotopurine derivatives and investigation of their antimicrobial activity and DNA interactions
Celik, Guelay Dilek,Disli, A Ali,Oener, Yagmur,Acik, Leyla
experimental part, p. 578 - 582 (2012/07/13)
A series of 6-thiocyanatopurine derivatives introduced with different alkyl groups in position 9 was synthesized. The structures of the synthesized compounds were evaluated via spectroscopic methods and elemental methods of analyses. All the synthesized compounds were screened for their antibacterial activities against Gram-positive and Gram-negative bacteria and for their antifungal activities against yeast strains. All the synthesized compounds showed better antibacterial activities against Gram-positive bacteria compared to Gram-negative bacteria. DNA interactions with pBR322 DNA were determined. Most of the compounds caused conformational changes in DNA.