194479-11-3

Basic information

• Product Name: Benzoic acid, 4-[(1H-benzimidazol-2-ylthio)methyl]-, ethyl ester
• CAS NO: 194479-11-3
• Molecular Formula: C17H16N2O2S
• Molecular Weight: 312.392
• Mol File: 194479-11-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-[(1H-benzimidazol-2-ylthio)methyl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-[(1H-benzimidazol-2-ylthio)methyl]-, ethyl ester(194479-11-3)
• EPA Substance Registry System: Benzoic acid, 4-[(1H-benzimidazol-2-ylthio)methyl]-, ethyl ester(194479-11-3)

Safety Data

• Hazardous Substances Data: 194479-11-3(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 194479-08-8 4-<(2'-thiobenzimidazol)methyl>benzoic acid 
• 1201-90-7 ethyl 4-chloromethylbenzoate 
• 15091-69-7 2-mercaptobenzimidazole sodium salt 

Relevant articles and documents

Benzimidazol-2-yl or benzimidazol-2-ylthiomethyl benzoylguanidines as novel Na+/H+ exchanger inhibitors, synthesis and protection against ischemic-reperfusion injury

A novel series of benzimidazol-2-yl or benzimidazol-2-ylthiomethyl benzoylguanidines were designed and synthesized as Na+/H+exchanger inhibitors. Most of them were found to inhibit NHE1-mediated platelet swelling in a concentration-dependent manner, and to have significant cardioprotective effect against myocardial ischemic-reperfusion injury, among which compounds 10a and 34 were more potent than cariporide in both in vivo and in vitro tests.