19547-88-7

Basic information

• Product Name: L-Cysteine, N-acetyl-,methyl ester, acetate (ester) (9CI)
• Synonyms: Cysteine,N-acetyl-, methyl ester, acetate (ester), L- (8CI); Acetic acid, thio-, S-esterwith N-acetyl-L-cysteine methyl ester; Mucothiol; N,S-Diacetylcysteine methylester
• CAS NO: 19547-88-7
• Molecular Formula: C₈H₁₃NO₄S
• Molecular Weight: 219.2581
• EINECS: 243-146-2
• Mol File: 19547-88-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 97-100℃
• Boiling Point: 379.4°Cat760mmHg
• Flash Point: 183.3°C
• Appearance: WHITE POWDER OR CRYSTALS
• Density: 1.208g/cm³
• Vapor Pressure: 5.85E-06mmHg at 25°C
• Refractive Index: 1.49
• PKA: 14.09±0.46(Predicted)
• CAS DataBase Reference: L-Cysteine, N-acetyl-,methyl ester, acetate (ester) (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: L-Cysteine, N-acetyl-,methyl ester, acetate (ester) (9CI)(19547-88-7)
• EPA Substance Registry System: L-Cysteine, N-acetyl-,methyl ester, acetate (ester) (9CI)(19547-88-7)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.
• WGK Germany: 3
• Hazardous Substances Data: 19547-88-7(Hazardous Substances Data)

Usage

Uses

Mucothiol, a cysteine derivative has been found to possess NDM-?1 inhibition activity. It also has been researched for reducing relapse of addictive behavior.

InChI:InChI=1/C8H13NO4S/c1-5(10)9-7(8(12)13-3)4-14-6(2)11/h7H,4H2,1-3H3,(H,9,10)/t7-/m0/s1

Upstream product

• 35356-70-8 Methyl 2-acetamidoacrylate 
• 507-09-5 tiolacetic acid 
• 7652-46-2 Ac-Cys-OMe 
• 616-91-1 N-acetylcystein 
• 75-36-5 acetyl chloride 
• 67-56-1 methanol 
• 52-89-1 l-cysteine hydrochloride 
• 108-24-7 acetic anhydride 
• 18598-63-5 L-cysteine methyl ester hydrochloride 

Downstream Products

• 7652-46-2 Ac-Cys-OMe 

Relevant articles and documents

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Chemoselective Synthesis of N-Terminal Cysteinyl Thioesters via β,γ-C,S Thiol-Michael Addition

Dehydroalanine (ΔAla) is a highly electrophilic residue that can react efficiently with sulfur nucleophiles to furnish cysteinyl analogues. Herein, we report an efficient synthesis of N-terminal cysteinyl thioesters, suitable for S,N-acyl transfer, based on β,γ-C,S thiol-Michael addition. Both ionic and radical-based methodologies were found to be efficient for this process.