195983-60-9 Usage
General Description
8-CHLORO-3,4-DIHYDRO-1H-BENZO[E][1,4]DIAZEPINE-2,5-DIONE is a chemical compound with a molecular formula of C16H10ClN3O2. It is a benzodiazepine derivative, a class of psychoactive drugs that are commonly used as sedatives and anxiolytics. This specific compound contains a chloro group and a dihydropyridine ring structure, and it is known for its sedative and anxiolytic properties. Benzodiazepines like 8-CHLORO-3,4-DIHYDRO-1H-BENZO[E][1,4]DIAZEPINE-2,5-DIONE act on the central nervous system, enhancing the inhibitory effects of the neurotransmitter gamma-aminobutyric acid (GABA) and producing a calming and relaxing effect. Despite their therapeutic uses, benzodiazepines can also be highly addictive and have the potential for abuse and dependence.
Check Digit Verification of cas no
The CAS Registry Mumber 195983-60-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,5,9,8 and 3 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 195983-60:
(8*1)+(7*9)+(6*5)+(5*9)+(4*8)+(3*3)+(2*6)+(1*0)=199
199 % 10 = 9
So 195983-60-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H7ClN2O2/c10-5-1-2-6-7(3-5)12-8(13)4-11-9(6)14/h1-3H,4H2,(H,11,14)(H,12,13)
195983-60-9Relevant articles and documents
Discovery and structure-activity relationships of imidazole-containing tetrahydrobenzodiazepine inhibitors of farnesyltransferase
Ding, Charles Z.,Batorsky, Roberta,Bhide, Rajeev,Chao, Hannguang J.,Cho, Young,Chong, Saeho,Gullo-Brown, Johnni,Guo, Peng,Kim, Soong Hoon,Lee, Frank,Leftheris, Katerina,Miller, Arthur,Mitt, Toomas,Patel, Manorama,Penhallow, Becky A.,Ricca, Carol,Rose, William C.,Schmidt, Robert,Slusarchyk, William A.,Vite, Gregory,Yan, Ning,Manne, Veeraswamy,Hunt, John T.
, p. 5241 - 5253 (2007/10/03)
2,3,4,5-Tetrahydro-1-(imidazol-4-ylalkyl)-1,4-benzodiazepines were found to be potent inhibitors of farnesyltransferase (FT). A hydrophobic substituent at the 4-position of the benzodiazepine, linked via a hydrogen bond acceptor, was important to enzyme i
