19614-12-1

Basic information

• Product Name: 2-BROMO-5-METHOXYBENZYL BROMIDE 97
• Synonyms: 2-BROMO-5-METHOXYBENZYL BROMIDE 97;4-Bromo-3-bromomethyl anisole;5-BroMo-2-Methoxy Benzyl BroMide;2-Bromo-5-methyoxybenzyl bromide;2-Bromo-5-methoxybenzyl bromide 97%
• CAS NO: 19614-12-1
• Molecular Formula: C₈H₈Br₂O
• Molecular Weight: 279.958
• Product Categories: Ethers;Organic Building Blocks;Oxygen Compounds;Building Blocks;C2 to C8;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;alkyl bromide
• Mol File: 19614-12-1.mol
• Article Data: 45

Chemical Properties

• Melting Point: 90-94 °C(lit.)
• Boiling Point: 299.6 °C at 760 mmHg
• Flash Point: 120.3 °C
• Appearance: White to beige/Solid
• Density: 1.759 g/cm³
• Vapor Pressure: 0.0021mmHg at 25°C
• Refractive Index: 1.584
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Water Solubility: Soluble in hot methanol. Slightly soluble in water.
• CAS DataBase Reference: 2-BROMO-5-METHOXYBENZYL BROMIDE 97(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-5-METHOXYBENZYL BROMIDE 97(19614-12-1)
• EPA Substance Registry System: 2-BROMO-5-METHOXYBENZYL BROMIDE 97(19614-12-1)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: Ⅱ
• Hazardous Substances Data: 19614-12-1(Hazardous Substances Data)

Usage

Uses

Employed as an important intermediate for raw material for organic synthesis, agrochemical, pharmaceutical and dyestuff field

InChI:InChI=1/C8H8Br2O/c1-11-7-2-3-8(10)6(4-7)5-9/h2-4H,5H2,1H3

Upstream product

• 591-31-1 3-methoxy-benzaldehyde 
• 77-48-5 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione 
• 27060-75-9 4-bromo-3-methylanisole 
• 150192-39-5 2-Bromo-5-methoxybenzyl alcohol 
• 128-08-5 N-Bromosuccinimide 
• 100-84-5 1-methoxy-3-methyl-benzene 
• 874-98-6 1-bromomethyl-3-methoxybenzene 

Downstream Products

• 220429-84-5 dimethyl [(2-bromo-5-methoxyphenyl)methyl]phosphonate 
• 613241-20-6 5-[(2-bromo-5-methoxy-benzyl)-methyl-amino]-1-ethyl-3-methyl-1H-pyrimidine-2,4-dione 
• 613241-24-0 5-[(2-bromo-5-methoxy-benzyl)-methyl-amino]-1,3-diethyl-1H-pyrimidine-2,4-dione 
• 484000-91-1 methyl 6-O-(tert-butyldimethylsilyl)-4-O-(2-bromo-5-methoxybenzyl)-2,3-O-isopropylidene-α-D-mannopyranoside 
• 869064-85-7 3-deoxy-3-(2-bromo-5-methoxybenzyl-para-toluenesulfonylamino)-1,2:5,6-di-O-isopropylidene-α-D-glucofuranoside 
• 866097-01-0 1-(2-bromo-5-methoxybenzyloxy)benzene 
• 262364-69-2 N-(2-bromo-5-methoxy-benzyl)-N-phenyl-hydrazine 
• 953424-03-8 C₁₆H₁₃BrO₂S 

Relevant articles and documents

Halogenolysis of Benzylcobaloximes

The reaction of substituted benzylcobaloximes p-RC6H4Co(dmgH)2-Py (R=OMe, NHCOCH3 and NMe2) and m-RC6H4CH2Co(dmgH)2Py (R=Me, OMe) with halogens (Cl2 and Br2) in chloroform under nitrogen forms ring substituted organic and organometallic products.

Discovery of orally active nonpeptide vitronectin receptor antagonists based on a 2-benzazepine Gly-Asp mimetic [2]

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Stereoselective Convergent Synthesis of Tetrahydro-5 H-benzo[c]fluorene via Nine-Membered Ring-Closing Metathesis and Transannular Acid-Mediated Cyclization/Nucleophilic Addition

The diene methyl ethers or acetates, constructed from the Li-Br exchange/addition reactions of 2-vinylbenzaldehydes and 2-(but-3-en-1-yl)bromoarenes followed by etherification or acetylation of the corresponding alcohols, smoothly underwent the ring-closi

CATALYSTS

A catalyst comprising (i) an asymmetric complex of formula (I) wherein M is zirconium or hafnium; each X is a sigma ligand; L is a divalent bridge selected from —R′2C—, —R′2C—CR′2—, —R′2Si—, —R′2Si—SiR′2—, —R′2Ge—, wherein each R′ is independently a hydrogen atom, C1-C20-alkyl, tri(C1-C20-alkyl)silyl, C6-C20-aryl, C7-C20-arylalkyl or C7-C20-alkylaryl; R2 and R2′ are each independently linear C1-10 hydrocarbyl; R5 and R5′ are each independently hydrogen or a C1-20 hydrocarbyl group; R6 and R6′ are each independently hydrogen or a C1-20 hydrocarbyl group; R7 is hydrogen or a C1-20 hydrocarbyl group or is ZR3; Z is O or S, preferably O; R3 is a C1-10 hydrocarbyl group; Ar is an aryl or heteroaryl group having up to 20 carbon atoms optionally substituted by one or more groups R8; Ar′ is an aryl or heteroaryl group having up to 20 carbon atoms optionally substituted by one or more groups R8′; and R8 and R8′ are each independently is a C1-20 hydrocarbyl group; with the proviso that at least one of R6 or R7 is not H; and (ii) a cocatalyst comprising a compound of a group 13 metal, e.g. boron.