19655-46-0 Usage
General Description
8-chloro-6-methylquinoline is a chemical compound with the molecular formula C10H8ClN. It is a chlorinated derivative of quinoline, and it consists of a quinoline ring with a chlorine atom at the 8th position and a methyl group at the 6th position. 8-chloro-6-methylquinoline is commonly used as a building block in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It possesses several potential biological activities, including antiviral and antimicrobial properties, and has been studied for its potential applications in drug development. Additionally, 8-chloro-6-methylquinoline is also utilized in the production of dyes, pigments, and other specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 19655-46-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,6,5 and 5 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 19655-46:
(7*1)+(6*9)+(5*6)+(4*5)+(3*5)+(2*4)+(1*6)=140
140 % 10 = 0
So 19655-46-0 is a valid CAS Registry Number.
19655-46-0Relevant articles and documents
From Anilines to Quinolines: Iodide- and Silver-Mediated Aerobic Double C?H Oxidative Annulation–Aromatization
Wu, Jiwei,Liao, Zhixiong,Liu, Dong,Chiang, Chien-Wei,Li, Zheng,Zhou, Zhonghao,Yi, Hong,Zhang, Xu,Deng, Zixin,Lei, Aiwen
supporting information, p. 15874 - 15878 (2017/10/23)
Quinoline synthesis from easily accessible raw materials such as anilines is a valuable and meaningful task. Herein, we communicate an iodide- and silver-mediated C?H/C?H oxidative annulation–aromatization between anilines and allyl alcohols. This protocol provides a direct route to the synthesis of quinoline derivatives from inexpensive commodities. Various kinds of anilines, even heterocyclic anilines, were shown to be workable substrates, generating the corresponding multi-substituted quinolines in good yields.
