197638-76-9

Basic information

• Product Name: 4-(4-ETHYLPIPERAZIN-1-YL)BENZALDEHYDE
• Synonyms: 4-(4-ETHYLPIPERAZIN-1-YL)BENZALDEHYDE;4-(4-ETHYLPIPERAZIN-1-YL)BENZALDEHYDE, 95+%;Zinc02563697
• CAS NO: 197638-76-9
• Molecular Formula: C₁₃H₁₈N₂O
• Molecular Weight: 218.29
• Mol File: 197638-76-9.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 364.624 °C at 760 mmHg
• Flash Point: 158.821 °C
• Appearance: /
• Density: 1.081 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.568
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 7.85±0.10(Predicted)
• CAS DataBase Reference: 4-(4-ETHYLPIPERAZIN-1-YL)BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-ETHYLPIPERAZIN-1-YL)BENZALDEHYDE(197638-76-9)
• EPA Substance Registry System: 4-(4-ETHYLPIPERAZIN-1-YL)BENZALDEHYDE(197638-76-9)

Safety Data

• Hazardous Substances Data: 197638-76-9(Hazardous Substances Data)

Usage

General Description

4-(4-ethylpiperazin-1-yl)benzaldehyde is a chemical compound with the molecular formula C15H20N2O. It is a benzaldehyde derivative that contains a piperazine ring with an ethyl group attached to it. 4-(4-ETHYLPIPERAZIN-1-YL)BENZALDEHYDE is commonly used in organic synthesis and medicinal chemistry, particularly in the development of pharmaceuticals and bioactive compounds. It is also used as a building block for the synthesis of various heterocyclic compounds. Additionally, 4-(4-ethylpiperazin-1-yl)benzaldehyde has been studied for its potential biological activities, including its antimicrobial and anti-cancer properties. It is important to handle this compound with caution, as with all chemicals, and according to proper safety protocols and regulations.

InChI:InChI=1/C13H18N2O/c1-2-14-7-9-15(10-8-14)13-5-3-12(11-16)4-6-13/h3-6,11H,2,7-10H2,1H3

Upstream product

• 623-00-7 4-bromobenzenecarbonitrile 
• 5308-25-8 4-ethylpiperazine 
• 459-57-4 4-fluorobenzaldehyde 
• 34421-94-8 4-bromobenzaldehyde diethyl acetal 
• 186650-78-2 4-(4-ethyl-piperazin-1-yl)-benzonitrile 

Downstream Products

• 197638-79-2 [4-(4-Ethyl-piperazin-1-yl)-benzyl]-methyl-amine 
• 1402709-64-1 3-((4-(6-chloro-2-(4-(4-ethylpiperazin-1-yl)phenyl)-3H-imidazo-[4,5-b]pyridin-7-yl)piperazin-1-yl)methyl)-5-methylisoxazole 
• 402745-30-6 [4-(4-ethylpiperazinyl)phenyl]methan-1-ol 
• 179328-89-3 N,N'-Diethyl-N-[4-(4-ethyl-piperazin-1-yl)-benzyl]-ethane-1,2-diamine 
• 197638-69-0 N'-Ethyl-N-[4-(4-ethyl-piperazin-1-yl)-benzyl]-N-methyl-ethane-1,2-diamine 
• 197638-81-6 (2-Chloro-ethyl)-[4-(4-ethyl-piperazin-1-yl)-benzyl]-methyl-amine 

Relevant articles and documents

Design, synthesis, and bioactivity investigation of novel benzimidazole derivatives as potent urease inhibitors

Herein, we synthesized a series of novel benzimidazole derivatives 5a–k and screened their bioactivity as potent urease inhibitors. The structure of the 5a–k was elucidated using spectroscopic technics (1H-NMR, 13C-NMR, MS), elementa

Multifunctional quinoxaline-hydrazone derivatives with acetylcholinesterase and monoamine oxidases inhibitory activities as potential agents against Alzheimer’s disease

Multitarget molecules are considered as an effective way for the treatment of AD, instead of the classic one-drug-one-target strategy because of the multifactorial nature of AD. A variety of studies indicate that several enzymes inhibitors can be useful in the treatment of AD, including acetylcholinesterase (AchE), butyrylcholinesterase (BuChE) and monoamine oxidase (MAO). Various substituted quinoxaline-hydrazone derivatives were synthesized, and their activity in vitro were investigated, including AChE/BuChE inhibitory activity and MAOA/B inhibitory activity. Based on the experimental results, compound 5l exhibited good inhibitory potency on both AchE (IC50 = 0.028 ± 0.001 μM) and monoamine oxidase B (IC50 = 0.046 ± 0.002 μM). Molecular modeling studies showed that 5l could bind to the active site of AChE and MAO-B. Taken together, these results suggested that compound 5l might be a potential multifunctional agent for the treatment of AD.

USE OF DISUBSTITUTED BENZENES TO CONTROL INSECTICIDE-RESISTANT PESTS

The invention is in the technical field of insect control and relates to the use of a disubstituted benzenes for controlling insecticide-resistant pests such as mosquitoes and cockroaches.