198277-56-4

Basic information

• Product Name: 1H-Indole-2-carboxylic acid, 5-bromo-1-(phenylmethyl)-, ethyl ester
• CAS NO: 198277-56-4
• Molecular Formula: C18H16BrNO2
• Molecular Weight: 358.235
• Mol File: 198277-56-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-Indole-2-carboxylic acid, 5-bromo-1-(phenylmethyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-2-carboxylic acid, 5-bromo-1-(phenylmethyl)-, ethyl ester(198277-56-4)
• EPA Substance Registry System: 1H-Indole-2-carboxylic acid, 5-bromo-1-(phenylmethyl)-, ethyl ester(198277-56-4)

Safety Data

• Hazardous Substances Data: 198277-56-4(Hazardous Substances Data)

Upstream product

• 16732-70-0 ethyl 5-bromoindolecarboxylate 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 

Downstream Products

• 1186429-65-1 ethyl 3-(acetyloxy)-1-benzyl-5-bromo-1H-indole-2-carboxylate 
• 481630-96-0 ethyl 1-benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indole-2-carboxylate 
• 711010-73-0 (1-benzyl-5-bromo-1H-indol-2-yl)-methanol 

Relevant articles and documents

Catalytic direct acetoxylation of indoles

(Chemical Equation Presented) 3-Acetoxyindole-2-carboxylates could be readily synthesized in a Pd(OAc)2- or PtCl2-catalyzed direct C-3 acetoxylation of indole-2-carboxylates using PhI(OAc)2 as a terminal oxidant.

SUBSTITUTED DIHYDROPYRANO INDOLE-3,4-DIONE DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1)

Compounds of formula (1) and II) are provided wherein: X is an alkali metal or a basic amine moiety; R1, is alkyl, cycloalkyl, -CH2--cycloalkyl, pyridinyl, -CH2-pyridinyl, phenyl or benzyl, the rings of these gr

HETEROCYCLIC BETA-ADRENERGIC AGONISTS

The present invention relates to certain compounds of the formula (I) the racemic-enantiomeric mixtures and optical isomers of said compounds and the pharmaceutically acceptable salts or prodrugs thereof, depicted below, which are β-adrenergic receptor agonists and accordingly have utility as, inter alia, hypoglycemic and antiobesity agents. More specifically, the compounds of the instant invention are selective agonists of β 3-adrenergic receptor. The invention also relates to methods of use for the compounds and to pharmaceutical compositions containing them. The compounds of the present invention also possess utility for increasing lean meat deposition and/or improving the lean meat to fat ratio in animals, e.g., ungulate animals, companion animals and poultry. The compounds have the formula STR1 wherein R. sup.1, R. sup.2, R 3, R 4, R 5, Y and Z are as defined in the specification.