198336-00-4

Basic information

• Product Name: (1R,5R,6R)-2-[6-(tert-butyldimethylsilanyloxymethyl)-5-isopropyl-2-methylcyclohex-2-enyl]acetaldehyde
• Synonyms: (1R,5R,6R)-2-[6-(tert-butyldimethylsilanyloxymethyl)-5-isopropyl-2-methylcyclohex-2-enyl]acetaldehyde
• CAS NO: 198336-00-4
• Molecular Weight: 324.579
• Mol File: 198336-00-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1R,5R,6R)-2-[6-(tert-butyldimethylsilanyloxymethyl)-5-isopropyl-2-methylcyclohex-2-enyl]acetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,5R,6R)-2-[6-(tert-butyldimethylsilanyloxymethyl)-5-isopropyl-2-methylcyclohex-2-enyl]acetaldehyde(198336-00-4)
• EPA Substance Registry System: (1R,5R,6R)-2-[6-(tert-butyldimethylsilanyloxymethyl)-5-isopropyl-2-methylcyclohex-2-enyl]acetaldehyde(198336-00-4)

Safety Data

• Hazardous Substances Data: 198336-00-4(Hazardous Substances Data)

Upstream product

• 198335-99-8 [(1R,5R,6R)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-5-isopropyl-2-methyl-cyclohex-2-enyl]-acetic acid ethyl ester 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 55449-13-3 (1S,4S,6S)-4-Isopropyl-1-methyl-7-oxa-bicyclo[4.1.0]heptan-2-one 
• 223790-28-1 Methanesulfonic acid (1S,2R,3S,4R,6S)-3-(tert-butyl-dimethyl-silanyloxymethyl)-4-isopropyl-1-methyl-7-oxa-bicyclo[4.1.0]hept-2-yl ester 
• 213674-83-0 (1S,3S,4R,6S)-3-(tert-Butyl-dimethyl-silanyloxymethyl)-4-isopropyl-1-methyl-7-oxa-bicyclo[4.1.0]heptan-2-one 
• 213674-91-0 (1R,2R,3S,4R,6S)-3-(tert-Butyl-dimethyl-silanyloxymethyl)-4-isopropyl-1-methyl-7-oxa-bicyclo[4.1.0]heptan-2-ol 
• 223762-88-7 (1S,3S,4R,6S)-3-Hydroxymethyl-4-isopropyl-1-methyl-7-oxa-bicyclo[4.1.0]heptan-2-one 
• 198335-98-7 (1S,4R,5R)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-5-isopropyl-2-methyl-cyclohex-2-enol 
• 39903-97-4 (S)-carvone oxide 
• 2244-16-8 (S)-p-mentha-6,8-dien-2-one 
• 1026090-92-5 (1R,5R,6R)-2-(6-hydroxymethyl-5-isopropyl-2-methylcyclohex-2-enyl)-N-methoxy-N-methylacetamide 
• 1027079-96-4 (4aR,8R,8aR)-8-isopropyl-5-methyl-1,4,4a,7,8,8a-hexahydroisochromen-3-one 
• 1028292-30-9 (1R,5R,6R)-2-[6-(tert-butyldimethylsilanyloxymethyl)-5-isopropyl-2-methylcyclohex-2-enyl]-N-methoxy-N-methylacetamide 

Downstream Products

• 201142-29-2 4-[(1R,5R,6R)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-5-isopropyl-2-methyl-cyclohex-2-enyl]-3-hydroxy-butan-2-one 
• 198336-03-7 (S)-1-[(1R,5R,6R)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-5-isopropyl-2-methyl-cyclohex-2-enyl]-but-3-en-2-ol 
• 198336-02-6 (E)-4-[(1R,5R,6R)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-5-isopropyl-2-methyl-cyclohex-2-enyl]-but-2-en-1-ol 
• 223762-75-2 (1R,2R,6R)-2-[(2S,3S)-3-Hydroxy-2-(4-methoxy-benzyloxy)-3-methyl-pent-4-ynyl]-6-isopropyl-3-methyl-cyclohex-3-enecarbaldehyde 
• 198336-04-8 tert-Butyl-{(1R,2R,6R)-6-isopropyl-2-[(S)-2-(4-methoxy-benzyloxy)-but-3-enyl]-3-methyl-cyclohex-3-enylmethoxy}-dimethyl-silane 
• 198336-05-9 (S)-4-[(1R,5R,6R)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-5-isopropyl-2-methyl-cyclohex-2-enyl]-3-(4-methoxy-benzyloxy)-butan-2-one 
• 198336-08-2 (Z)-2-Hydroxymethyl-3-{(1S,2R,6R)-6-isopropyl-2-[(2S,3S)-2-(4-methoxy-benzyloxy)-3-methyl-3-trimethylsilanyloxy-pent-4-ynyl]-3-methyl-cyclohex-3-enyl}-propenal 
• 223762-76-3 (E)-2-Cyano-3-{(1S,2R,6R)-2-[(2S,3S)-3-hydroxy-2-(4-methoxy-benzyloxy)-3-methyl-pent-4-ynyl]-6-isopropyl-3-methyl-cyclohex-3-enyl}-acrylic acid ethyl ester 
• 198336-11-7 C₃₇H₅₆O₅Si 
• 198336-07-1 (E)-2-Cyano-3-{(1S,2R,6R)-6-isopropyl-2-[(2S,3S)-2-(4-methoxy-benzyloxy)-3-methyl-3-trimethylsilanyloxy-pent-4-ynyl]-3-methyl-cyclohex-3-enyl}-acrylic acid ethyl ester 
• 198336-12-8 (Z)-(1R,4S,5R,9R,11S,12S)-5-Isopropyl-11-(4-methoxy-benzyloxy)-8,12-dimethyl-2-triisopropylsilanyloxymethyl-15-oxa-tricyclo[10.2.1.0^4,9]pentadeca-2,7,13-trien-1-ol 
• 198336-13-9 Triisopropyl-[(Z)-(1R,4S,5R,9R,11S,12S)-5-isopropyl-1-methoxy-11-(4-methoxy-benzyloxy)-8,12-dimethyl-15-oxa-tricyclo[10.2.1.0^4,9]pentadeca-2,7,13-trien-2-ylmethoxy]-silane 
• 213675-31-1 C₄₀H₆₄O₅Si₂ 
• 198336-09-3 (Z)-3-{(1S,2R,6R)-6-Isopropyl-2-[(2S,3S)-2-(4-methoxy-benzyloxy)-3-methyl-3-trimethylsilanyloxy-pent-4-ynyl]-3-methyl-cyclohex-3-enyl}-2-triisopropylsilanyloxymethyl-propenal 

Relevant articles and documents

A convergent approach to the marine natural product eleutherobin: Synthesis of key intermediates and attempts to produce the basic skeleton

Synthesis of (1R,5R,6R)-2-(6-hydroxymethyl-5-isopropyl-2-methylcyclohex-2-enyl)-N-methoxy-N-m ethylacetamide 8 from R-(-)-phellandrene in six steps, and (3aR*,4S*,6R*,6aS*)-(6-hydroxymethyl-4-methoxy-2,2,6-tri methyl-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)acetic acid methyl ester 17 from tetrabromoacetone and 2-methoxy-5-methyl-furan in six steps, provided two key fragments which have been combined to produce intermediates for attempted construction of the basic skeleton of eleutherobin.

Synthesis of the tricyclic core of eleutherobin and sarcodictyins and total synthesis of sarcodictyin A

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