198711-26-1

Basic information

• Product Name: pyrimidin-2-yl-p-tolyl-amine
• Synonyms: pyrimidin-2-yl-p-tolyl-amine
• CAS NO: 198711-26-1
• Molecular Weight: 185.228
• Mol File: 198711-26-1.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: pyrimidin-2-yl-p-tolyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: pyrimidin-2-yl-p-tolyl-amine(198711-26-1)
• EPA Substance Registry System: pyrimidin-2-yl-p-tolyl-amine(198711-26-1)

Safety Data

• Hazardous Substances Data: 198711-26-1(Hazardous Substances Data)

Upstream product

• 275-03-6 tetrazolo[1,5-a]pyrimidine 
• 108-88-3 toluene 
• 109-12-6 2-aminopyrimidine 
• 106-38-7 para-bromotoluene 
• 1722-12-9 2-chloropyrimidine 
• 106-49-0 p-toluidine 
• 4595-60-2 2-bromopyrimidine 

Downstream Products

• 1402816-36-7 1-acetyl-1-tert-butyl-3-pyrimidin-2-yl-3-p-tolyl-urea 

Relevant articles and documents

Asymmetric pyrene derivatives comprising amine group including heteroaryl group and organic light-emitting diode including the same

The present invention relates to a pyrene derivative represented by [chemical formula A] or [chemical formula B], and an organic light emitting diode comprising the same, wherein substituents Py_1, Py_2, Ar_1, Ar_2, Z, and m are defined in the detailed de

Insights on bimetallic micellar nanocatalysis for buchwald-hartwig aminations

A nanocatalyst for micellar Buchwald-Hartwig aminations is developed, thoroughly characterized, and applied on a variety of substrates. The catalyst is stable under ambient conditions for at least six months. The catalyst retained its activity after several cycles, and its structure remained intact as confirmed by NMR spectroscopy. Association of Pd nanoparticles with Cu by a phosphine ligand is revealed by 31P NMR spectroscopy, and their linkage with the activated carbon surface is revealed by XAS analysis. Control NMR experiments revealed the binding of the ligand with both Cu and Pd, and all phosphine molecules are under the same environment. In addition to NMR and XAS analysis, the catalyst is characterized by SEM, HRTEM, XPS, and TGA. Reactions are highly reproducible at variable scales. Environmentally benign, proline-based amphiphile PS-750-M is critical for catalytic activity, which is achieved under mild conditions in water as the reaction medium. The inherent sustainability of these conditions coupled with a low E factor achievable through robust recycling of catalyst and reaction medium demonstrates the significant utility of this technology.

Multiple Roles of the Pyrimidyl Group in the Rhodium-Catalyzed Regioselective Synthesis and Functionalization of Indole-3-carboxylic Acid Esters

A regioselective synthesis of indole-3-carboxylic acid esters from anilines and diazo compounds has been realized by making use of the pyrimidyl group-assisted rhodium-catalyzed C-H activation and C-N bond formation. The reaction proceeds under mild conditions, exhibits good functional group tolerance and scalability. Reutilization of the pyrimidyl directing group in the resulting products provided an efficient strategy for further C-7 functionalization of indoles. Moreover, the pyrimidyl moiety could be readily removed as a leaving group to offer various free N-H indoles.