198781-66-7Relevant articles and documents
Intramolecular carbolithiation reactions for the preparation of 3-alkenylpyrrolidines.
Coldham, Iain,Price, Kathy N,Rathmell, Richard E
, p. 2111 - 2119 (2003)
Tin-lithium exchange allows the formation of alpha-amino-organolithium species that undergo anionic cyclization onto allylic ethers to give 3-alkenylpyrrolidines. The methodology has been applied to the synthesis of an advanced intermediate related to the natural product (-)-alpha-kainic acid.