19885-52-0Relevant articles and documents
Novel epitetrathiodioxopiperazines, emethallicins B and C, as potent inhibitors of compound 48/80-induced histamine release, from Emericella heterothallica
Kawahara, Nobuo,Nozawa, Koohei,Nakajima, Shoichi,Kawai, Ken-Ichi,Yamazaki, Mikio
, p. 951 - 952 (2007/10/02)
The structure elucidation of emethallicins B (1) and C (2), novel epitetrathiodioxopiperazines, possessing strong inhibitory activity of the histamine release from mast cells, isolated from the mycelial extract of Emericella heterothallica (mating type a), is reported, based on their 1H and 13C n.m.r. spectra and a chemical correlation of emethallicin A (10) with apoaranotin (11); they are diesters of two C 6-C2 acids having the same basic skeletons as apoaranotin (11) and aranotin (13), respectively.
