19927-28-7

Basic information

• Product Name: Thiocyanic acid, (4-methoxyphenyl)methyl ester
• CAS NO: 19927-28-7
• Molecular Formula: C9H9NOS
• Molecular Weight: 179.243
• Mol File: 19927-28-7.mol
• Article Data: 32

Chemical Properties

• CAS DataBase Reference: Thiocyanic acid, (4-methoxyphenyl)methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Thiocyanic acid, (4-methoxyphenyl)methyl ester(19927-28-7)
• EPA Substance Registry System: Thiocyanic acid, (4-methoxyphenyl)methyl ester(19927-28-7)

Safety Data

• Hazardous Substances Data: 19927-28-7(Hazardous Substances Data)

Upstream product

• 83318-10-9 C₂₆H₂₄NOS⁽¹⁺⁾*CNS^(1-) 
• 540-72-7 sodium thiocyanide 
• 105-13-5 4-Methoxybenzyl alcohol 
• 1147550-11-5 ammonium thiocyanate 
• 14629-56-2 trimethyl(4-methoxybenzyloxy)silane 
• 163276-49-1 1-thiocyanatopyrrolidine-2,5-dione 
• 6258-60-2 p-methoxybenzylmercaptan 
• 104-93-8 p-methylanizole 
• 2746-25-0 p-Methoxybenzyl bromide 
• 824-94-2 p-methoxybenzyl chloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 76950-80-6 1-(4-Methoxy-benzyl)-2-methylsulfanyl-4,6-diphenyl-pyridinium; iodide 
• 3674-54-2 tetrabutylammonium thiocyanate 
• 333-20-0 potassium thioacyanate 

Downstream Products

• 17004-42-1 1,2-bis(4-methoxybenzyl)disulfide 
• 6258-60-2 p-methoxybenzylmercaptan 
• 210626-08-7 3-iodo-6-methoxy-4-(4-methoxybenzylthio)-1H-2-benzothiopyran 
• 210626-00-9 bis(4-methoxybenzylthio)acetylene 
• 3694-57-3 1-(isothiocyanatomethyl)-4-methoxybenzene 

Relevant articles and documents

PEG-DIL-based MnCl42?: A novel phase transfer catalyst for nucleophilic substitution reactions of benzyl halides

Poly(ethylene glycol) dicationic ionic liquid-based MnCl42? was prepared by nucleophilic substitution of poly(ethylene glycol) dichloride with methylimidazole followed by reaction with MnCl2. The structural properties of the catalyst were systematically investigated using Fourier transform infrared, UV–visible and Raman spectra and thermogravimetric analysis. The application of this catalyst allows the synthesis of a variety of benzyl thiocyanates and azides in high yield under reflux conditions in water. The main advantages of this method are its easy nature, rapidity, environmental benignity and high yields.

Sulfuryl Fluoride Promoted Thiocyanation of Alcohols: A Practical Method for Preparing Thiocyanates

A novel SO 2F 2-promoted thiocyanation method for the one-step synthesis of thiocyanates through C-O bond cleavage of readily available alcohols with ammonium thiocyanate as the thiocyanating agent was developed. The method avoids the use of additional catalyst, and a variety of (hetero)arene, alkene and aliphatic alcohols reacted with high efficiency in ethyl acetate under mild conditions to afford the corresponding thiocyanates in excellent to quantitative yields with broad functional-group compatibility.

Direct Photocatalytic S-H Bond Cyanation with Green cN Source

Herein we report a novel C-S bond cleavage and reconstruction strategy for the synthesis of thiocyanates through direct photocatalytic S-H bond cyanation from thiols and inorganic thiocyanate salts. In our strategy, the unprecedented example of cutting off C-S bond of SCN- to deliver the green CN sources is demonstrated. This transformation features nontoxic and inexpensive CN sources, available starting materials, metal-/base-/ligand-/peroxide-free, high step economy and mild conditions. It leads to the construction of various thiocyanates and some medicinally and biologically active thiocyanate-containing molecules.